{"id":"W2044687526","doi":"10.1073/pnas.0804876105","title":"Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas","year":2008,"lang":"en","type":"letter","venue":"Proceedings of the National Academy of Sciences","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Progenitor cell; CD31; Angiogenesis; Progenitor; Cancer research; Haematopoiesis; Bone marrow; Biology; Medicine; Stem cell; Pathology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000356339,0.0002349938,0.0003729314,0.000155373,0.0001754489,0.00001564117,0.0005923768,0.0003714289,0.000005280475],"category_scores_gemma":[0.0001125851,0.0001771944,0.0003717733,0.0001945758,0.001008778,0.00001931888,0.00009289145,0.0001463687,1.920881e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001762167,"about_ca_system_score_gemma":0.0001087124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009838606,"about_ca_topic_score_gemma":9.55391e-8,"domain_scores_codex":[0.9979779,0.0000191173,0.0004725649,0.0004804469,0.0008186692,0.0002313307],"domain_scores_gemma":[0.9980345,0.00006622389,0.001367352,0.0000214598,0.0004773378,0.00003312726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008835815,0.00002874793,0.0001928089,0.0005065424,0.0001423437,1.649431e-7,0.00008275196,0.00002598844,0.9785973,0.00005212596,0.02019181,0.00009107806],"study_design_scores_gemma":[0.0003426809,0.0001547507,0.0003520279,0.0001324385,0.000176767,0.00002560379,0.000104456,0.0000630277,0.9930718,0.0002999731,0.005089974,0.0001864904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9666384,0.005550196,0.00005561413,0.02485135,0.0001026344,0.0009898981,0.001740716,0.000005582366,0.00006554322],"genre_scores_gemma":[0.9887992,0.000511038,0.002008931,0.006683488,0.001555915,0.00009606219,0.00001646602,0.00002644922,0.0003024266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02216076,"threshold_uncertainty_score":0.7225779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03195606621066582,"score_gpt":0.2724450950096601,"score_spread":0.2404890287989943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}