{"id":"W2044697354","doi":"10.1016/j.cellsig.2013.09.008","title":"Notch activation augments nitric oxide/soluble guanylyl cyclase signaling in immortalized ovarian surface epithelial cells and ovarian cancer cells","year":2013,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; University of Alberta","funders":"","keywords":"Soluble guanylyl cyclase; Ovarian cancer; Cell biology; Cancer research; Signal transduction; Stromal cell; Cancer cell; Biology; Notch signaling pathway; Nitric oxide; Chemistry; Cancer; Endocrinology; Guanylate cyclase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000258437,0.0002044958,0.0002875737,0.0003457058,0.0002447519,0.0004359232,0.0001928379,0.0002411866,0.001915133],"category_scores_gemma":[0.0002136747,0.0001468404,0.0003148735,0.0003236873,0.0002496011,0.0002933905,0.0002978914,0.000675501,0.0002868169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002779014,"about_ca_system_score_gemma":0.0003018519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001349185,"about_ca_topic_score_gemma":0.002110313,"domain_scores_codex":[0.9996897,0.000064825,0.00003987746,0.00003040704,0.00007863897,0.00009652606],"domain_scores_gemma":[0.9998335,0.00006337647,0.00001539483,0.00003496915,0.00001949447,0.00003322079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000578473,0.00008346025,0.0004765112,0.00004252987,0.000007779006,0.0001682939,0.00008770314,0.00005135422,0.9967741,0.0002441813,0.00007976093,0.00140582],"study_design_scores_gemma":[0.00006922291,0.0004054709,0.009958033,0.000008091406,0.00002277993,0.0002808042,0.0002138208,0.0008337034,0.9836441,0.0001031958,0.004455106,0.000005814326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996514,0.0008767653,0.0005357893,0.00009744755,0.00003534847,0.00001697006,0.0003608666,0.00002144822,0.001541369],"genre_scores_gemma":[0.9943599,0.0006437239,0.0005444344,0.00006122557,0.0000126442,0.00003150997,0.001014312,0.000007192656,0.003324953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001915133,"threshold_uncertainty_score":0.006406724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01511660125030849,"score_gpt":0.2426090354907376,"score_spread":0.2274924342404291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}