{"id":"W2044699118","doi":"10.1007/s00428-012-1266-3","title":"Transdifferentiation of pituitary thyrotrophs to lactothyrotrophs in primary hypothyroidism: case report","year":2012,"lang":"en","type":"article","venue":"Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Thyrotropic cell; Internal medicine; Endocrinology; Prolactin; Hormone; Transdifferentiation; Hyperplasia; Thyroid; Thyrotropin-releasing hormone; Adenoma; Biology; Pituitary gland; Somatotropic cell; Medicine; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006173553,0.002711356,0.001980437,0.003376604,0.003728929,0.001902604,0.002717739,0.006809353,0.004832959],"category_scores_gemma":[0.003469385,0.002008764,0.00226305,0.002171737,0.003303198,0.002717,0.003218644,0.004298412,0.001718708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002188267,"about_ca_system_score_gemma":0.0007610302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001691903,"about_ca_topic_score_gemma":0.001663128,"domain_scores_codex":[0.9987691,0.0001019216,0.0001582565,0.0003360803,0.0001566611,0.0004779515],"domain_scores_gemma":[0.9954874,0.001704586,0.0005513146,0.0008061925,0.0002277346,0.001222719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00008514029,0.00001871094,0.002104962,0.00003880445,0.000009705173,0.9952592,0.000123642,0.00002273418,0.001663376,0.0001108284,0.00007086369,0.0004919175],"study_design_scores_gemma":[0.00003347014,0.00006672616,0.002572736,0.000005825348,0.00002959973,0.9949569,0.0001326036,0.0001986939,0.00144527,0.0001425923,0.0004030251,0.00001252778],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799072,0.004769616,0.003673635,0.001654622,0.0004553226,0.000145807,0.0002291302,0.0003185644,0.008846093],"genre_scores_gemma":[0.9946734,0.0006705896,0.001270296,0.0004220422,0.001173542,0.00004077679,0.0001073251,0.00003616381,0.001605886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006809353,"threshold_uncertainty_score":0.01616782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03105891770087905,"score_gpt":0.3416660080701847,"score_spread":0.3106070903693056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}