{"id":"W2044847825","doi":"10.1021/jp061939v","title":"Characterization of Nucleobase−Amino Acid Stacking Interactions Utilized by a DNA Repair Enzyme","year":2006,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Allison University; University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation","keywords":"Stacking; Nucleobase; Aromatic amino acids; Chemistry; Crystallography; Amino acid; DNA; Stereochemistry; Active site; Enzyme; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001402622,0.0001478218,0.000216216,0.000009241782,0.00005829196,0.00001150123,0.0002649303,0.00007516713,0.00004957245],"category_scores_gemma":[0.0000534095,0.0001119088,0.000242882,0.00007670643,0.0001244416,0.00001240944,0.00006845094,0.0001900157,0.000001633134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002168993,"about_ca_system_score_gemma":0.00004850181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000453317,"about_ca_topic_score_gemma":3.977586e-7,"domain_scores_codex":[0.9991108,0.00003619486,0.0003694679,0.000123478,0.0002048904,0.0001551677],"domain_scores_gemma":[0.9989981,0.0000249373,0.0004871058,0.0002689468,0.0001624658,0.0000584508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000205883,0.0002481041,0.00005260215,0.00004332825,0.00006656397,0.000001713406,0.00004093764,0.000009459951,0.9968258,0.0000037985,0.002358018,0.0001437698],"study_design_scores_gemma":[0.0004469753,0.00007353577,0.0001288694,0.00003765022,0.00007855047,0.00004686277,0.00006386168,0.0001283497,0.9898475,0.00003592522,0.009002144,0.0001097242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979683,0.0001010179,0.0003828107,0.0001060728,0.00004066412,0.00003873162,0.00004601823,0.000009334927,0.001307009],"genre_scores_gemma":[0.9982111,0.00002594114,0.00003860899,0.0000387391,0.0008327693,0.000001411025,0.0001014746,0.00001913524,0.0007307631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006978271,"threshold_uncertainty_score":0.4563507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005175968395670767,"score_gpt":0.2277810714447746,"score_spread":0.2226051030491038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}