{"id":"W2044863101","doi":"10.1002/jmr.851","title":"Cleavage of the human thyrotropin receptor by ADAM10 is regulated by thyrotropin","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular Recognition","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cegep de Sept Iles","funders":"Szegedi Tudományegyetem; Magyar Tudományos Akadémia; Semmelweis Egyetem","keywords":"Ectodomain; ADAM10; Thyrotropin receptor; Disintegrin; Chemistry; Receptor; Cleavage (geology); Metalloproteinase; Protein subunit; Biochemistry; Molecular biology; Enzyme; Biology; Endocrinology; Thyroid; Graves' disease; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002097477,0.0002863478,0.0002129219,0.000109101,0.0001171546,0.0002348596,0.0001126518,0.0001881322,0.001451186],"category_scores_gemma":[0.0001843189,0.0001324783,0.0003380779,0.00009587322,0.000196106,0.0001367646,0.0001577407,0.0004088132,0.0004916506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001858361,"about_ca_system_score_gemma":0.000116212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002654691,"about_ca_topic_score_gemma":0.0003672852,"domain_scores_codex":[0.9997801,0.00005175899,0.00002630428,0.00003685843,0.00005737318,0.00004762631],"domain_scores_gemma":[0.9998862,0.00003338477,0.00002923062,0.00001138326,0.00001622364,0.00002361779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001706882,0.00001868742,0.0002174951,0.00003637722,0.000005897726,0.0001428099,0.00002473647,0.00002945583,0.9986938,0.00003028329,0.00003548909,0.0005941837],"study_design_scores_gemma":[0.00001975007,0.0002336888,0.007699472,0.000005583812,0.000009596976,0.0006439709,0.00004862419,0.0006288664,0.9890355,0.0000274978,0.001642344,0.00000498495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953324,0.001414389,0.001879016,0.00009039349,0.00003266544,0.00003056819,0.0002509884,0.00002934028,0.0009401691],"genre_scores_gemma":[0.9934296,0.0007441773,0.002423997,0.00005268029,0.00001280624,0.00004088169,0.0006627336,0.000009901231,0.002623134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001451186,"threshold_uncertainty_score":0.004854739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01680847841596665,"score_gpt":0.2972416634797808,"score_spread":0.2804331850638141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}