{"id":"W2044884455","doi":"10.1038/cgt.2008.18","title":"Vaccination of fiber-modified adenovirus-transfected dendritic cells to express HER-2/neu stimulates efficient HER-2/neu-specific humoral and CTL responses and reduces breast carcinogenesis in transgenic mice","year":2008,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CTL*; Transgene; Transfection; HER2/neu; Virology; Cancer research; Vaccination; Genetically modified mouse; Carcinogenesis; Biology; Immunology; Molecular biology; Medicine; Immune system; Cell culture; Breast cancer; Gene; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002976663,0.0004845848,0.0003771208,0.0003915969,0.0001550316,0.0002855479,0.0002675553,0.0005406778,0.0009846565],"category_scores_gemma":[0.0001847539,0.0002376881,0.0003425577,0.0001504665,0.0002950522,0.0002937837,0.0001439367,0.001145331,0.0003449604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004292011,"about_ca_system_score_gemma":0.0002927701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009450561,"about_ca_topic_score_gemma":0.0009870093,"domain_scores_codex":[0.9997616,0.00003630273,0.00001558068,0.00004437743,0.0000468593,0.00009518679],"domain_scores_gemma":[0.9998114,0.0000470415,0.0000431067,0.00003192286,0.00001696293,0.00004960576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002513629,0.0001780011,0.0001039725,0.00001233046,0.000005793232,0.00001754223,0.00001148308,0.00007308341,0.9985301,0.00008908899,0.00003832623,0.000688738],"study_design_scores_gemma":[0.000105689,0.001342724,0.001872145,0.000005671056,0.00002908091,0.000143964,0.0000177627,0.001383131,0.9940726,0.0000668316,0.0009557399,0.000004675617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966407,0.0002969322,0.001943484,0.00008276825,0.00005783806,0.0000385376,0.000140373,0.00007496946,0.0007244095],"genre_scores_gemma":[0.9949602,0.000356368,0.001726139,0.00006791162,0.00003289351,0.00004209805,0.0003792802,0.00003349551,0.002401678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009846565,"threshold_uncertainty_score":0.003294051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02549797599296659,"score_gpt":0.2616586213519168,"score_spread":0.2361606453589502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}