{"id":"W2044884455","doi":"10.1038/cgt.2008.18","title":"Vaccination of fiber-modified adenovirus-transfected dendritic cells to express HER-2/neu stimulates efficient HER-2/neu-specific humoral and CTL responses and reduces breast carcinogenesis in transgenic mice","year":2008,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CTL*; Transgene; Transfection; HER2/neu; Virology; Cancer research; Vaccination; Genetically modified mouse; Carcinogenesis; Biology; Immunology; Molecular biology; Medicine; Immune system; Cell culture; Breast cancer; Gene; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000263696,0.0003810057,0.0006139819,0.0003966541,0.0002614144,0.00002116242,0.0002609888,0.0002559416,0.0003945442],"category_scores_gemma":[0.000007778297,0.0003616744,0.0001080615,0.0004078371,0.0002906577,0.00009740123,0.0000281308,0.0002150217,0.00001080676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008188332,"about_ca_system_score_gemma":0.0001425884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004905285,"about_ca_topic_score_gemma":0.00003519622,"domain_scores_codex":[0.9976214,0.00065441,0.0005612065,0.000571675,0.00008928344,0.0005020065],"domain_scores_gemma":[0.9990449,0.0003361534,0.0001130324,0.0003250257,0.0001313626,0.00004954819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01273119,0.0002515566,0.0007447292,0.00003384922,0.0001687677,0.00000726902,0.006366346,0.0007826283,0.9589627,0.000005388669,0.00006568484,0.01987987],"study_design_scores_gemma":[0.004441306,0.0005065303,0.1256754,0.00008414133,0.00002403992,0.0001217243,0.0002261054,0.000009992829,0.8675814,0.000006260693,0.0009755393,0.0003475991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8712791,0.1272208,0.00003972598,0.000189537,0.0003685055,0.0006750473,0.0001723336,0.00004416974,0.00001080521],"genre_scores_gemma":[0.9754043,0.02361648,0.00006191302,0.0001012144,0.0000372879,0.0001218353,0.0000220396,0.00005382316,0.0005811462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1249306,"threshold_uncertainty_score":0.9998835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02549797599296659,"score_gpt":0.2616586213519168,"score_spread":0.2361606453589502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}