{"id":"W2044945977","doi":"10.1016/j.virol.2013.11.032","title":"Residues R199H200 of prototype foamy virus transactivator Bel1 contribute to its binding with LTR and IP promoters but not its nuclear localization","year":2013,"lang":"en","type":"article","venue":"Virology","topic":"Parvovirus B19 Infection Studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Natural Science Foundation of Tianjin City; National Natural Science Foundation of China; University of Washington","keywords":"Transactivation; Biology; Promoter; Transcription (linguistics); Nuclear transport; Nuclear localization sequence; Transcription factor; DNA; Molecular biology; Gene; DNA-binding protein; Viral replication; Cell nucleus; Virus; Genetics; Virology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001336226,0.0001751361,0.0004562767,0.0002020538,0.0001151961,0.00001218733,0.00005259051,0.0001295011,0.000166203],"category_scores_gemma":[0.0001587598,0.0001379729,0.00003074954,0.000237168,0.0001251119,0.0001573965,0.00002771573,0.000144183,0.0002635534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004542129,"about_ca_system_score_gemma":0.00003842817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001476957,"about_ca_topic_score_gemma":0.00004251801,"domain_scores_codex":[0.9988819,0.00007962716,0.0002734678,0.0002997752,0.0001758056,0.0002894386],"domain_scores_gemma":[0.9992814,0.00007180774,0.0001176385,0.0001529161,0.0002392894,0.0001369706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002555422,0.0001584944,0.005753505,0.0002207385,0.0003017655,0.00002208485,0.001212229,0.00002952657,0.9871075,0.0001877478,0.0008212054,0.00162979],"study_design_scores_gemma":[0.004883196,0.004379824,0.1459451,0.0002062006,0.0002749835,0.0001844279,0.0001978684,0.0006092326,0.8266066,0.00002944162,0.01629658,0.0003864698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993969,0.00009875838,0.001390848,0.001770881,0.00005933546,0.002257714,0.00003105035,0.00008297763,0.0003394436],"genre_scores_gemma":[0.9981571,0.00006539205,0.0002251292,0.001005224,0.00004697762,0.0002280837,0.000004983987,0.00003421587,0.0002328902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1605009,"threshold_uncertainty_score":0.5626372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01911275421591195,"score_gpt":0.262043865018926,"score_spread":0.242931110803014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}