{"id":"W2044971407","doi":"10.1038/cgt.2013.60","title":"Potent CD4+ T-cell epitope P30 enhances HER2/neu-engineered dendritic cell-induced immunity against Tg1-1 breast cancer in transgenic FVBneuN mice by enhanced CD4+ T-cell-stimulated CTL responses","year":2013,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"CTL*; Epitope; Cancer research; Cd4 t cell; Transgene; T cell; Immunity; Genetically modified mouse; Dendritic cell; Cell; Biology; Immune system; Cell biology; Chemistry; Immunology; CD8; Antibody; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005236178,0.001096376,0.00124236,0.0004425931,0.0005627373,0.0001145058,0.001247464,0.0008612894,0.003823418],"category_scores_gemma":[0.00002060726,0.001027673,0.0004373929,0.0008289067,0.0003683911,0.0004629414,0.00008191537,0.001292524,0.0004522327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000493789,"about_ca_system_score_gemma":0.0007635046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005818496,"about_ca_topic_score_gemma":0.0002042215,"domain_scores_codex":[0.9941134,0.001674135,0.001245485,0.00109216,0.0001959816,0.001678834],"domain_scores_gemma":[0.9975154,0.0005110404,0.0004337738,0.001056391,0.0003536057,0.0001298065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005557737,0.001006242,0.0001154648,0.00007566517,0.000416565,0.000008465114,0.002327839,0.0004988486,0.9553672,8.58784e-7,0.00119842,0.03342668],"study_design_scores_gemma":[0.009985576,0.0006347981,0.005449088,0.0001897848,0.0000664364,0.00002244597,0.0006263048,0.00004199173,0.978113,0.00001195867,0.003645443,0.001213156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8324763,0.1625392,0.0001072371,0.0006851545,0.001824856,0.001518073,0.0004616784,0.0002093384,0.0001781096],"genre_scores_gemma":[0.9005373,0.09025463,0.00003967044,0.001099651,0.0001060546,0.00102134,0.0002042039,0.0001875254,0.006549623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07228461,"threshold_uncertainty_score":0.9992173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01058547897533864,"score_gpt":0.2430021621283436,"score_spread":0.232416683153005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}