{"id":"W2044992166","doi":"10.1165/rcmb.2014-0158oc","title":"The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm","year":2014,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Air Quality and Health Impacts","field":"Environmental Science","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Coastal Health Research Institute; Vancouver General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Inflammasome; Innate immune system; Leucine-rich repeat; Acquired immune system; Immune system; Receptor; Biology; Leucine; Cell biology; Immunology; Genetics; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002047153,0.0004515764,0.0003672043,0.0001865051,0.0002230467,0.0004364322,0.0001929133,0.0005012061,0.001310259],"category_scores_gemma":[0.0001376647,0.0001233874,0.0004829238,0.0001382114,0.0003945083,0.0003522334,0.0003535033,0.000879986,0.0004000642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003181105,"about_ca_system_score_gemma":0.0003376979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004245091,"about_ca_topic_score_gemma":0.000619963,"domain_scores_codex":[0.9996943,0.00005130705,0.0000291478,0.00008014992,0.00007659441,0.0000684544],"domain_scores_gemma":[0.9998857,0.00001061744,0.0000452938,0.00001083687,0.0000129974,0.00003460396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001916766,0.00002353688,0.0009282362,0.00006338378,0.000005609259,0.0001703377,0.00002120228,0.00003650657,0.9972261,0.0000695745,0.00004307231,0.001220787],"study_design_scores_gemma":[0.00008034846,0.001143219,0.1188494,0.00005190447,0.00007427757,0.003335379,0.0002465004,0.002205474,0.8669979,0.0005668495,0.006424836,0.00002399827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831432,0.006522884,0.006772565,0.000360956,0.00008970796,0.00006686815,0.000733942,0.0002326031,0.002077329],"genre_scores_gemma":[0.9936594,0.001584489,0.002768619,0.0001606009,0.00002709179,0.00006630355,0.0003914931,0.00001835975,0.00132362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001310259,"threshold_uncertainty_score":0.004383266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0107973122681216,"score_gpt":0.2516819616226101,"score_spread":0.2408846493544885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}