{"id":"W2044992166","doi":"10.1165/rcmb.2014-0158oc","title":"The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm","year":2014,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Air Quality and Health Impacts","field":"Environmental Science","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Coastal Health Research Institute; Vancouver General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Inflammasome; Innate immune system; Leucine-rich repeat; Acquired immune system; Immune system; Receptor; Biology; Leucine; Cell biology; Immunology; Genetics; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001881904,0.0002422233,0.0004135413,0.0001023683,0.0002604807,0.0000433746,0.0002901676,0.00009951113,0.0002864802],"category_scores_gemma":[0.00023357,0.0001607582,0.00009713478,0.0002511837,0.0008158915,0.0001147357,0.0002064563,0.0003273135,0.0002099672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009344232,"about_ca_system_score_gemma":0.00005604302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000587734,"about_ca_topic_score_gemma":0.00002046148,"domain_scores_codex":[0.9968083,0.001358783,0.0007099155,0.0003205173,0.0002496169,0.0005528482],"domain_scores_gemma":[0.9983624,0.000258498,0.0005908532,0.0003367016,0.00005770469,0.000393812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002380228,0.00004531666,0.01575875,0.00001393428,0.00004585987,0.00003667368,0.0006343711,0.0001059766,0.968802,0.00005980716,0.0008747337,0.01124235],"study_design_scores_gemma":[0.002138283,0.0161015,0.1262153,0.0001488458,0.00007420734,0.00007233556,0.002241862,0.00001252917,0.5138741,0.0009483104,0.3372138,0.000958912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992425,0.0003406604,0.001096593,0.005592236,0.00009556487,0.0002544007,0.000008350314,0.00001026612,0.000176885],"genre_scores_gemma":[0.9871001,0.00004780286,0.002189029,0.0102495,0.00008026006,0.00002611997,9.4105e-7,0.00002666635,0.0002796423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4549279,"threshold_uncertainty_score":0.6555528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0107973122681216,"score_gpt":0.2516819616226101,"score_spread":0.2408846493544885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}