{"id":"W2044994598","doi":"10.1186/s12865-014-0045-0","title":"The change in Ig regulation from children to adults disconnects the correlation with the 3’RR hs1.2 polymorphism","year":2014,"lang":"en","type":"article","venue":"BMC Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"Ministero della Salute","keywords":"Allele; Biology; Immune system; Antibody; Allele frequency; Immunoglobulin heavy chain; Immunology; Gene; Genetics; Genotype; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000161769,0.0002892488,0.0002096275,0.0005156875,0.0001973212,0.0003382639,0.0002598508,0.0003956408,0.004597762],"category_scores_gemma":[0.0007229845,0.0001136752,0.0002888492,0.0004672243,0.0002704183,0.0001474912,0.0002332063,0.0004163402,0.0005016749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001215293,"about_ca_system_score_gemma":0.0001258818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009391141,"about_ca_topic_score_gemma":0.0005701507,"domain_scores_codex":[0.999769,0.00003188227,0.00002322014,0.0001032347,0.00003448729,0.00003812963],"domain_scores_gemma":[0.9991148,0.000200607,0.00042245,0.00005591147,0.000068519,0.0001377589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001319096,0.00006941692,0.9631137,0.00005957833,0.0001022996,0.0008695099,0.0003842441,0.00005251305,0.02461814,0.0001201836,0.0002825036,0.009008741],"study_design_scores_gemma":[0.000005960141,0.0001491336,0.9959125,0.000006806273,0.00002730898,0.001776706,0.00006643221,0.00003810482,0.001482038,0.00004189907,0.0004889809,0.000004091363],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985409,0.0003717214,0.0001520776,0.00003577366,0.000007880563,0.000002833636,0.0004120645,0.00001067887,0.0004661673],"genre_scores_gemma":[0.9988507,0.0001127475,0.000151139,0.00002389266,0.00001271367,0.000005176512,0.000408099,0.000007730448,0.0004276816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004597762,"threshold_uncertainty_score":0.01538104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00828249778843459,"score_gpt":0.1959141672016172,"score_spread":0.1876316694131826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}