{"id":"W2045066818","doi":"10.1016/j.celrep.2013.07.015","title":"XIAP Regulates Caspase Activity in Degenerating Axons","year":2013,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"XIAP; Cell biology; Caspase; Biology; Nerve growth factor; Neuroscience; Inhibitor of apoptosis; Caspase-9; Apoptosis; Programmed cell death; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001620575,0.0002266424,0.0001767367,0.0002462826,0.0001938897,0.0004425427,0.0001658263,0.0002236726,0.0006764189],"category_scores_gemma":[0.0001700688,0.0001080184,0.0001765664,0.0001309167,0.000359855,0.0004657655,0.0002351643,0.0004971824,0.0002741155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003689741,"about_ca_system_score_gemma":0.0001912563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002952503,"about_ca_topic_score_gemma":0.0003681712,"domain_scores_codex":[0.9998847,0.00001833415,0.00001583662,0.00002543936,0.00003100693,0.00002468309],"domain_scores_gemma":[0.9998603,0.00003156147,0.0000481709,0.00001285062,0.00001941944,0.00002764571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004651592,0.000005776192,0.0007120789,0.00002911461,0.000002250139,0.00009568079,0.00002622807,0.00006242275,0.9975615,0.0001496532,0.00001072278,0.001298068],"study_design_scores_gemma":[0.00001048173,0.0001391697,0.02308222,0.00001357389,0.00001270828,0.0008696085,0.00008668467,0.001172598,0.9728485,0.0004524665,0.00130635,0.000005701824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895378,0.006198634,0.003010796,0.00008492068,0.00001140096,0.000005457972,0.00009507981,0.00004464771,0.001011331],"genre_scores_gemma":[0.9943674,0.002989986,0.001623038,0.00002047415,0.000006284744,0.000006211264,0.0001037517,0.000007031105,0.0008758626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006764189,"threshold_uncertainty_score":0.002677083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007341948657572321,"score_gpt":0.2121922905683018,"score_spread":0.2048503419107295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}