{"id":"W2045066818","doi":"10.1016/j.celrep.2013.07.015","title":"XIAP Regulates Caspase Activity in Degenerating Axons","year":2013,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"XIAP; Cell biology; Caspase; Biology; Nerve growth factor; Neuroscience; Inhibitor of apoptosis; Caspase-9; Apoptosis; Programmed cell death; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475369,0.0001091343,0.00009842249,0.00003493574,0.00005791959,0.00002837103,0.00003740029,0.0001325246,0.00007631467],"category_scores_gemma":[0.00002716447,0.0001002328,0.00005308064,0.0000588843,0.00002040581,0.000005916862,0.0000560722,0.00005765578,0.000008659077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000013922,"about_ca_system_score_gemma":0.00004032025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002258142,"about_ca_topic_score_gemma":0.00005714936,"domain_scores_codex":[0.9991988,0.00003078953,0.0001931732,0.0003080147,0.00008178975,0.000187446],"domain_scores_gemma":[0.9994508,0.000004866977,0.0001145429,0.0003204758,0.00004453593,0.00006480202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000002895474,0.00004252483,0.00193668,0.00001009009,0.00000331195,0.00003565385,0.00001589385,0.0003663804,0.9919568,0.000007764835,0.0006304441,0.004991584],"study_design_scores_gemma":[0.0001065678,0.00003939098,0.005733301,0.00000692032,0.00000433301,0.00007146096,0.00001549456,0.0006501972,0.9907134,0.0001788539,0.00234678,0.0001332893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955615,0.0003086651,0.000613003,0.00003799276,0.0001888543,0.000219308,5.231304e-7,0.00001116286,0.003059019],"genre_scores_gemma":[0.9947236,0.00003968622,0.0009065467,0.00003287895,0.0001282556,0.0000335177,0.00004357066,0.00001614181,0.004075767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004858294,"threshold_uncertainty_score":0.4087376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007341948657572321,"score_gpt":0.2121922905683018,"score_spread":0.2048503419107295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}