{"id":"W2045067655","doi":"10.1111/j.1747-0285.2007.00533.x","title":"Formation Pathways and Opioid Activity Data for 3‐Hydroxypyridinium Compounds Derived from Glucuronic Acid and Opioid Peptides by Maillard Processes","year":2007,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Glucuronic acid; Moiety; Stereochemistry; Opioid peptide; Peptide; Opioid receptor; Amino acid; Opioid; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003474372,0.0005460586,0.0002003328,0.0002070811,0.0001389477,0.0001710071,0.0001502517,0.000307093,0.0009828288],"category_scores_gemma":[0.0003036307,0.000143808,0.000366788,0.0001769795,0.0002104002,0.0002515395,0.0001066214,0.0003595863,0.0002549257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002068127,"about_ca_system_score_gemma":0.0001110449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002221999,"about_ca_topic_score_gemma":0.0001788816,"domain_scores_codex":[0.9998447,0.00005645373,0.00001226779,0.00002855198,0.00003276865,0.00002519773],"domain_scores_gemma":[0.9995944,0.0001454652,0.0001308505,0.00003709644,0.00004887977,0.00004333218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002174905,0.00001592911,0.0002690428,0.00006170724,0.00001065872,0.00004816859,0.00003140617,0.0001306048,0.9976065,0.00008934932,0.00001033773,0.001508723],"study_design_scores_gemma":[0.000004726327,0.0002889072,0.001466116,0.000002532169,0.00001139731,0.0001301861,0.000007616998,0.000342956,0.9973984,0.00002847175,0.0003150927,0.00000362822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882978,0.003449555,0.006887757,0.000023808,0.00001079241,0.00003906741,0.0001991191,0.00003752468,0.001054577],"genre_scores_gemma":[0.9893467,0.001343731,0.007352655,0.00002924051,0.0000142368,0.0000554864,0.0006594816,0.00001588569,0.001182729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009828288,"threshold_uncertainty_score":0.003287852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05912137548332686,"score_gpt":0.2756198808618233,"score_spread":0.2164985053784964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}