{"id":"W2045067655","doi":"10.1111/j.1747-0285.2007.00533.x","title":"Formation Pathways and Opioid Activity Data for 3‐Hydroxypyridinium Compounds Derived from Glucuronic Acid and Opioid Peptides by Maillard Processes","year":2007,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Glucuronic acid; Moiety; Stereochemistry; Opioid peptide; Peptide; Opioid receptor; Amino acid; Opioid; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002609786,0.0002794916,0.0003701375,0.00003946515,0.0002125677,0.00005874636,0.0004835553,0.0001696457,0.000004999909],"category_scores_gemma":[0.0006734796,0.0002366834,0.00003373299,0.0001179927,0.0005607368,0.0003948457,0.0004281186,0.0002191033,0.000007665204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002573132,"about_ca_system_score_gemma":0.00005252345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001163179,"about_ca_topic_score_gemma":0.000004485053,"domain_scores_codex":[0.9981056,0.0001100929,0.0002869742,0.0009091677,0.00008095063,0.0005071717],"domain_scores_gemma":[0.9976424,0.001620214,0.0001738928,0.0003634449,0.0000450059,0.0001550496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003849747,0.00006831522,0.00008042739,0.00007175167,0.000007828306,0.000002628063,0.0001036249,2.155591e-7,0.9944112,0.00007198609,0.001712165,0.003084937],"study_design_scores_gemma":[0.0006494003,0.0002082082,0.0001176106,0.00001880572,0.00002312135,0.00001889002,0.00003761753,0.0004652294,0.9901108,0.002942404,0.005142511,0.0002654214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921951,0.0006470236,0.005786223,0.0001500211,0.00008900948,0.0004674212,0.0005227381,0.00009513739,0.00004735662],"genre_scores_gemma":[0.9967379,0.000734994,0.001377961,0.0006738559,0.0001358957,0.00002758658,0.0002775553,0.00002615934,0.000008079031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004542844,"threshold_uncertainty_score":0.965167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05912137548332686,"score_gpt":0.2756198808618233,"score_spread":0.2164985053784964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}