{"id":"W2045072511","doi":"10.1016/j.phrs.2011.05.006","title":"North American ginseng protects the heart from ischemia and reperfusion injury via upregulation of endothelial nitric oxide synthase","year":2011,"lang":"en","type":"article","venue":"Pharmacological Research","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"National Institutes of Health; China Scholarship Council; Ontario Ministry of Research and Innovation; Ontario Ministry of Research, Innovation and Science","keywords":"Enos; Ginseng; LY294002; Protein kinase B; Nitric oxide; Downregulation and upregulation; Pharmacology; Endothelial nitric oxide synthase; Medicine; Nitric oxide synthase; Reperfusion injury; Endocrinology; Apoptosis; Internal medicine; Chemistry; Ischemia; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006182028,0.0001201392,0.0001529669,0.00003916535,0.000210387,0.00001281851,0.0002435496,0.00008766379,0.00007525156],"category_scores_gemma":[0.0004197188,0.00007107542,0.00005738319,0.0002892615,0.0006927481,0.000004094273,0.0003067655,0.000326701,0.00001042024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001253077,"about_ca_system_score_gemma":0.00003764144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004623109,"about_ca_topic_score_gemma":0.00001903982,"domain_scores_codex":[0.9984536,0.0004427093,0.000190923,0.0003931054,0.0002247068,0.0002949958],"domain_scores_gemma":[0.9991622,0.0002497934,0.00007334934,0.0002428071,0.0001400626,0.0001317607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004298655,0.0001553167,0.007914774,0.000005906029,0.00002128142,0.000001608894,0.0000186683,0.000002509481,0.9803401,0.00002434244,0.0003647957,0.01072089],"study_design_scores_gemma":[0.00022139,0.0004646211,0.1562459,0.000003663318,0.00001180235,0.00000233137,0.00002141824,0.0002381514,0.8402349,0.0001821638,0.002285348,0.00008836044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983169,0.0001352749,0.0003026747,0.0002331158,0.00001265784,0.0007070212,0.00004912662,0.00001494929,0.0002283102],"genre_scores_gemma":[0.9984512,0.0002327262,0.00072028,0.0001682804,0.0001233416,0.0002213186,0.00003178687,0.00000942585,0.00004168538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1483311,"threshold_uncertainty_score":0.2898372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0661042767080535,"score_gpt":0.3671116039234306,"score_spread":0.301007327215377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}