{"id":"W2045183567","doi":"10.1186/1742-4690-6-11","title":"HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome","year":2009,"lang":"en","type":"article","venue":"Retrovirology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Wellcome Trust","keywords":"Nuclear transport; Importin; Biology; Integrase; Virology; Reverse transcriptase; Viral replication; DNA; Nuclear localization sequence; Provirus; Cell nucleus; RNA; Virus; Genome; Cell biology; Gene; Genetics; Human immunodeficiency virus (HIV)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001464979,0.0003898126,0.0001428313,0.0001914901,0.0001736267,0.00039278,0.0003388324,0.0002999707,0.0006772023],"category_scores_gemma":[0.0001073777,0.0001063957,0.0001885174,0.0001403895,0.0003181087,0.0002746829,0.0003094147,0.000506257,0.0003742971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000409202,"about_ca_system_score_gemma":0.0001717632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002832518,"about_ca_topic_score_gemma":0.0004884506,"domain_scores_codex":[0.9999086,0.00001180899,0.000007302796,0.00001968809,0.00003072892,0.00002185773],"domain_scores_gemma":[0.9999093,0.00001990931,0.00002726065,0.00001502152,0.00001270605,0.00001570942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002328907,0.00001615698,0.0002729133,0.00002567528,0.000003872405,0.0000489072,0.000008858082,0.00005525178,0.99812,0.0002662648,0.00002949649,0.001129141],"study_design_scores_gemma":[0.000003997122,0.00007243705,0.001192241,0.000004260363,0.00000850472,0.0003275633,0.00001287778,0.0009166683,0.9953108,0.00007202409,0.00207546,0.000003028261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864927,0.001371004,0.009059842,0.0001226401,0.00002028119,0.00003553158,0.0002293546,0.000146562,0.002522196],"genre_scores_gemma":[0.990351,0.0006578747,0.006484495,0.00004744673,0.000007837679,0.00002094821,0.000536372,0.00003675053,0.001857332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006772023,"threshold_uncertainty_score":0.002968967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006162908518255798,"score_gpt":0.2154926512874497,"score_spread":0.2093297427691939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}