{"id":"W2045202324","doi":"10.1016/j.molbiopara.2010.05.005","title":"Characterization of a novel tyramine-gated chloride channel from Haemonchus contortus","year":2010,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Nematode management and characterization studies","field":"Agricultural and Biological Sciences","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ontario Institute of Technology; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ontario Institute of Technology","keywords":"Haemonchus contortus; Homomeric; Biology; Chloride channel; Receptor; Protein subunit; Ionotropic effect; Octopamine (neurotransmitter); Molecular biology; Biochemistry; Nematode; Gene; Serotonin; Glutamate receptor; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003878598,0.0001246306,0.0002292809,0.00001253693,0.00005244634,0.00001721104,0.0001102361,0.0001360885,0.0000519018],"category_scores_gemma":[0.0000312018,0.00005923784,0.00004783731,0.0001273671,0.00012828,0.00003686065,0.00007874454,0.00009072719,0.000003188959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002096545,"about_ca_system_score_gemma":0.000002022862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008016049,"about_ca_topic_score_gemma":0.00002723408,"domain_scores_codex":[0.9992902,0.00001313831,0.0002028298,0.0002488181,0.00009133732,0.0001536673],"domain_scores_gemma":[0.999686,0.00003550292,0.0001071486,0.00005342933,0.00005928433,0.0000586351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004809744,0.0000772008,0.003962317,0.000004879825,0.00002819955,0.00000382553,0.00002372006,3.027645e-8,0.9944763,0.0002716413,0.0000162578,0.001087588],"study_design_scores_gemma":[0.0002571268,0.0000430505,0.1214622,0.000005953754,0.00002331156,0.000004258664,0.00001882643,0.00008048851,0.8769115,0.00008444778,0.0009854423,0.0001233554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983816,0.00002935,0.0002197483,0.00081317,0.0001623605,0.0001293848,0.00008014193,0.00003359908,0.0001506463],"genre_scores_gemma":[0.9989172,0.00002140778,0.00004436523,0.0002761188,0.0001047895,0.000009341198,0.00059816,0.000001176585,0.00002748982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1175647,"threshold_uncertainty_score":0.2415649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01149417010692348,"score_gpt":0.2322137051416625,"score_spread":0.220719535034739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}