{"id":"W2045243021","doi":"10.1136/ebm.13.2.52","title":"Combined HRT increased CV events more than placebo but did not differ from oestrogen HRT after menopause","year":2008,"lang":"en","type":"letter","venue":"Evidence-Based Medicine","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Menopause; Placebo; Medicine; Postmenopausal women; Hormone replacement therapy (female-to-male); Gynecology; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0008726857,0.002143951,0.003814128,0.0009347762,0.0003728042,0.00004345476,0.0007902103,0.001772277,0.004080859],"category_scores_gemma":[0.002108393,0.00149898,0.0001832068,0.0006097347,0.0007564671,0.0003616727,0.0001852409,0.003522535,0.0007115842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001457938,"about_ca_system_score_gemma":0.002124773,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009005411,"about_ca_topic_score_gemma":0.00004509087,"domain_scores_codex":[0.9885454,0.0008291905,0.00220121,0.002190035,0.004018952,0.002215265],"domain_scores_gemma":[0.9904503,0.002725228,0.001149781,0.003054136,0.0005353836,0.00208512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.02806459,0.0008958855,0.05659842,0.00262605,0.002003693,0.02999626,0.0005300721,0.000001875404,0.005398838,0.000001390571,0.8732478,0.0006351089],"study_design_scores_gemma":[0.1225326,0.0417862,0.4448362,0.07312772,0.01504132,0.0007376226,0.00008976118,0.0002129858,0.006225493,0.0001175229,0.291534,0.003758501],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.4522584,0.007142204,0.00004454393,0.5337461,0.001478187,0.004028605,0.0008513223,0.0003222509,0.0001283852],"genre_scores_gemma":[0.3742573,0.00204738,0.0004616326,0.5988199,0.01005191,0.001039509,0.006268338,0.0003994496,0.00665464],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.5817138,"threshold_uncertainty_score":0.9995236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06222562232440169,"score_gpt":0.3194232577502422,"score_spread":0.2571976354258405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}