{"id":"W2045271912","doi":"10.1182/blood-2014-01-548651","title":"UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Université Laval; Hôpital de l'Enfant-Jésus; Centre hospitalier universitaire de Québec; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"BMI1; Haematopoiesis; Stem cell; Progenitor cell; Biology; Gene knockdown; Cell biology; Polycomb-group proteins; Hematopoietic stem cell; Cancer research; Cell culture; Genetics; Gene; Repressor; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007379852,0.0004006672,0.0002178952,0.0003370267,0.0002715132,0.0003161872,0.0003232247,0.0002565631,0.001207703],"category_scores_gemma":[0.00009997883,0.0001446108,0.0001999048,0.0002951425,0.0001891611,0.000207059,0.0002996472,0.000349697,0.0007587441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004031809,"about_ca_system_score_gemma":0.0002150173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005905874,"about_ca_topic_score_gemma":0.0006923856,"domain_scores_codex":[0.9999169,0.000007866941,0.000006849233,0.00002883783,0.00002759525,0.00001194098],"domain_scores_gemma":[0.9999404,0.000004645276,0.00002187997,0.000005024062,0.000006142018,0.00002185332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009730113,0.00001130764,0.0005338187,0.00006218797,0.000006774021,0.0001444963,0.000008830532,0.00009854371,0.9952768,0.000152506,0.0001402353,0.003467113],"study_design_scores_gemma":[0.00003510087,0.0001634238,0.02382693,0.00001330499,0.00003596871,0.001805896,0.00002674041,0.003876465,0.9467589,0.0002217058,0.02321501,0.00002041866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9513808,0.0140853,0.02480134,0.0004284184,0.0001240659,0.0000908815,0.003361327,0.0009231017,0.004804783],"genre_scores_gemma":[0.9782024,0.002669631,0.008461083,0.0001030447,0.00004086895,0.00005796679,0.004400548,0.00007906598,0.005985493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001207703,"threshold_uncertainty_score":0.004040182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109261989683536,"score_gpt":0.2494405004806889,"score_spread":0.2385143015123353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}