{"id":"W2045277695","doi":"10.2174/1566524023362159","title":"Toll-like Receptor 9, CpG DNA and Innate Immunity","year":2002,"lang":"en","type":"review","venue":"Current Molecular Medicine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"TLR9; Innate immune system; Toll-Like Receptor 9; CpG site; Biology; Acquired immune system; Immune system; Pattern recognition receptor; CpG Oligodeoxynucleotide; Toll-like receptor; Immunity; Cell biology; Innate lymphoid cell; Immunology; Intrinsic immunity; DNA methylation; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024538,0.001041713,0.0008533677,0.001009495,0.000303922,0.0008120899,0.0006707062,0.001090427,0.004709349],"category_scores_gemma":[0.0002629356,0.0001869754,0.0002131012,0.001325323,0.0003486375,0.001244438,0.0004085512,0.001079457,0.004689198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005378395,"about_ca_system_score_gemma":0.000859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006339977,"about_ca_topic_score_gemma":0.001156036,"domain_scores_codex":[0.9998732,0.00002266046,0.00001201618,0.00002346025,0.00005448698,0.00001418392],"domain_scores_gemma":[0.999928,0.00002090525,0.00001211376,0.000002484676,0.00002006502,0.00001637926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001793038,0.0001339741,0.0003373708,0.01021754,0.00004496934,0.0008154276,0.00007552106,0.0004094839,0.008978011,0.004611402,0.03982361,0.9343734],"study_design_scores_gemma":[0.0000219308,0.00009316757,0.001027232,0.000969693,0.00002721805,0.00226648,0.00006654418,0.00005599528,0.000870653,0.003361064,0.9912277,0.00001243882],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002752226,0.9960179,0.0001939414,0.0002258113,0.0005150124,0.000006904139,0.00001329335,0.00001130792,0.002740695],"genre_scores_gemma":[0.001925562,0.9897003,0.000408682,0.0004073252,0.0006334385,0.00001276312,0.00005639281,0.00000209415,0.006853495],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004709349,"threshold_uncertainty_score":0.0157544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03914635005385671,"score_gpt":0.3178656534169143,"score_spread":0.2787193033630576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}