{"id":"W2045288098","doi":"10.1097/shk.0b013e31822d6442","title":"The Toll-like Receptor 9 Ligand CPG-C Attenuates Acute Inflammatory Cardiac Dysfunction","year":2011,"lang":"en","type":"article","venue":"Shock","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Ejection fraction; Medicine; TLR9; Ischemia; CpG site; Internal medicine; Endocrinology; Chemistry; Gene expression; Heart failure; Gene; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003861476,0.0001591311,0.0001773281,0.00005860856,0.0004784029,0.00002316636,0.0001992661,0.0002263086,0.0003767364],"category_scores_gemma":[0.00004906205,0.0001103853,0.0001259776,0.00008551561,0.0001550908,0.0001676298,0.00007172241,0.0002336126,0.00444176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004066468,"about_ca_system_score_gemma":0.00006217275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003882677,"about_ca_topic_score_gemma":0.00001103361,"domain_scores_codex":[0.9989349,0.0002252315,0.0002833108,0.0001925698,0.00003927442,0.0003246781],"domain_scores_gemma":[0.9992927,0.0001143869,0.0001157666,0.0003776083,0.00008274155,0.00001684911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001150203,0.00002571018,0.002085104,0.000009477149,0.0006929471,0.000003539483,0.00150394,4.143417e-7,0.8840238,0.001546189,0.08227961,0.02667904],"study_design_scores_gemma":[0.0003959079,0.000125006,0.006913188,0.00001404656,0.00006923821,0.00001402781,0.000384616,0.000001521945,0.5286529,0.0001931894,0.4630853,0.0001510767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850959,0.003294537,0.00009645388,0.0003452129,0.004560709,0.0003079083,0.00001040942,0.0001403901,0.006148475],"genre_scores_gemma":[0.9559435,0.001331017,0.00005350561,0.0001722618,0.0001769544,0.0001023864,0.0001486242,0.00003750241,0.04203427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3808056,"threshold_uncertainty_score":0.9963334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019125787410086,"score_gpt":0.2028290552996484,"score_spread":0.1926377974255475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}