{"id":"W2045297932","doi":"10.1074/jbc.m309227200","title":"Role of the Epidermal Growth Factor Receptor in Signaling Strain-dependent Activation of the Brain Natriuretic Peptide Gene","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Epidermal growth factor; Endocrinology; Internal medicine; Epidermal growth factor receptor; Apocynin; Biology; Muscle hypertrophy; Growth factor; Chemistry; Molecular biology; Cell biology; Cancer research; Receptor; NADPH oxidase; Biochemistry; Oxidative stress; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003768302,0.00009920395,0.0003386609,0.00002006627,0.00002835841,0.000004356385,0.0001622878,0.0001761143,0.00004579052],"category_scores_gemma":[0.000757903,0.0000453849,0.0003889122,0.0001314415,0.00009693216,0.00002773826,0.00005359939,0.0004506109,1.716726e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001173652,"about_ca_system_score_gemma":0.0001436502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009672466,"about_ca_topic_score_gemma":2.183665e-7,"domain_scores_codex":[0.9988424,0.00005311413,0.0005736209,0.0001002667,0.0003022732,0.0001283465],"domain_scores_gemma":[0.9990363,0.0001295147,0.0005007214,0.000122528,0.0001578224,0.0000530806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001219004,0.00009016434,0.01399367,0.00005126974,0.00003252897,7.960138e-7,0.0001098635,0.0009865777,0.9843947,0.000007055224,0.000006518213,0.0002049968],"study_design_scores_gemma":[0.000786141,0.00007058263,0.08774584,0.0003515468,0.00001974472,0.00005999952,0.0002921062,0.00001662579,0.9102265,0.0003703762,0.00001316103,0.00004739627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979931,0.0002844592,0.00004997292,0.001403113,0.00005189236,0.0000928307,0.00001611684,0.000002384793,0.0001061807],"genre_scores_gemma":[0.999263,0.00004269333,0.000355353,0.00009901753,0.0002172075,5.927202e-7,0.000001957731,0.000005676683,0.000014465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07416818,"threshold_uncertainty_score":0.1957705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0198393221770592,"score_gpt":0.2497449138683958,"score_spread":0.2299055916913366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}