{"id":"W2045316963","doi":"10.1089/108497804773391757","title":"Molecular Imaging and Treatment of Malignant Gliomas Following Adenoviral Transfer of the Herpes Simplex Virus-Thymidine Kinase Gene and the Somatostatin Receptor Subtype 2 Gene","year":2004,"lang":"en","type":"article","venue":"Cancer Biotherapy and Radiopharmaceuticals","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Somatostatin receptor; Genetic enhancement; Herpes simplex virus; Multiplicity of infection; Somatostatin receptor 2; Glioma; Somatostatin; Thymidine kinase; Cancer research; Cell culture; Radionuclide therapy; In vivo; Biology; Molecular biology; Virology; Medicine; Virus; Internal medicine; Endocrinology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002668981,0.0002386385,0.0003309016,0.00004618822,0.0001413213,0.00002428041,0.0001490178,0.00008695144,0.00002255487],"category_scores_gemma":[0.000009892966,0.000139942,0.0001505295,0.0001547072,0.0007614631,0.000008774112,0.00003695691,0.00006101911,1.660964e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000303652,"about_ca_system_score_gemma":0.000123937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001197356,"about_ca_topic_score_gemma":0.00003218344,"domain_scores_codex":[0.9986758,0.0002038832,0.0002913586,0.0003549929,0.0001818032,0.0002921762],"domain_scores_gemma":[0.9994653,0.00003591854,0.00006256759,0.0002776918,0.0000444096,0.0001141161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003647487,0.00009162102,0.0005308196,0.00003572434,0.0003817371,0.000007741615,0.0004435363,0.00005149273,0.9597226,0.00009836746,0.000005863782,0.03498303],"study_design_scores_gemma":[0.007972076,0.0006332885,0.0003120366,0.00003366207,0.00009139535,0.00001643673,0.00005930596,0.00006821215,0.9872754,0.00007159664,0.00330244,0.0001641648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.867228,0.1300133,0.0001739862,0.001853212,0.00006757159,0.000545777,0.0001073804,0.000005450348,0.000005260159],"genre_scores_gemma":[0.9370244,0.06205888,0.0001485826,0.0005737098,0.00008335031,0.00005410931,0.000008153434,0.00003504697,0.000013781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06979636,"threshold_uncertainty_score":0.5706668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01796847720985809,"score_gpt":0.3231898402396126,"score_spread":0.3052213630297544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}