{"id":"W2045316963","doi":"10.1089/108497804773391757","title":"Molecular Imaging and Treatment of Malignant Gliomas Following Adenoviral Transfer of the Herpes Simplex Virus-Thymidine Kinase Gene and the Somatostatin Receptor Subtype 2 Gene","year":2004,"lang":"en","type":"article","venue":"Cancer Biotherapy and Radiopharmaceuticals","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Somatostatin receptor; Genetic enhancement; Herpes simplex virus; Multiplicity of infection; Somatostatin receptor 2; Glioma; Somatostatin; Thymidine kinase; Cancer research; Cell culture; Radionuclide therapy; In vivo; Biology; Molecular biology; Virology; Medicine; Virus; Internal medicine; Endocrinology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001058856,0.0002454799,0.0001754805,0.0001241819,0.00007871806,0.0001730968,0.0001371156,0.0002362761,0.0007744912],"category_scores_gemma":[0.00006909573,0.00008228455,0.0001661779,0.0001089825,0.000139619,0.0001506776,0.00007880894,0.0002261955,0.0001725318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002312344,"about_ca_system_score_gemma":0.0001513636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001148827,"about_ca_topic_score_gemma":0.000816344,"domain_scores_codex":[0.9999304,0.00001215958,0.000004043065,0.00001232897,0.00001880348,0.00002224708],"domain_scores_gemma":[0.9999852,0.000004684661,0.000003012939,0.000001988937,0.000001940523,0.000003255353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001961384,0.00004139967,0.00009787799,0.00007932814,0.000005079657,0.00007636592,0.00002039879,0.0001147041,0.9939329,0.0001467782,0.00006180733,0.005227263],"study_design_scores_gemma":[0.00002867175,0.0008289436,0.002257382,0.000004865724,0.00001970707,0.0003873831,0.00001886781,0.0009578201,0.9915619,0.00004133795,0.003887699,0.000005307997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809585,0.009345879,0.006032295,0.0001043916,0.00007523443,0.00005837226,0.0001360917,0.00009523682,0.003193918],"genre_scores_gemma":[0.988075,0.003845509,0.005119254,0.00004537882,0.00001646571,0.00004926929,0.0002385635,0.00001745114,0.002593258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001148827,"threshold_uncertainty_score":0.002590954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01796847720985809,"score_gpt":0.3231898402396126,"score_spread":0.3052213630297544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}