{"id":"W2045339365","doi":"10.1021/ol0160708","title":"Construction of Azaspirocyclic Ketones through α-Hydroxyiminium Ion or α-Siloxy Epoxide Semipinacol Rearrangements","year":2001,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Epoxide; Ion; Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002675598,0.0004833851,0.0002429399,0.0002140573,0.0001734047,0.0003166373,0.0003725816,0.0001815906,0.001731606],"category_scores_gemma":[0.0002282554,0.000146799,0.0002319873,0.0001932449,0.0002769605,0.0003080175,0.0003805852,0.0004994555,0.0006562236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002166717,"about_ca_system_score_gemma":0.0002298922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001864555,"about_ca_topic_score_gemma":0.0004428504,"domain_scores_codex":[0.9998616,0.00002931309,0.00001335593,0.00002627398,0.0000341918,0.00003521068],"domain_scores_gemma":[0.9998633,0.00002251056,0.00004113609,0.00001891454,0.00001781673,0.00003645429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001949764,0.00005293347,0.0002579979,0.0001330278,0.00002241577,0.0004679145,0.00007774181,0.000550389,0.9861888,0.002701381,0.0002495002,0.009102914],"study_design_scores_gemma":[0.00004551899,0.0004635825,0.001409037,0.000009611183,0.00002267714,0.0007765831,0.00003982353,0.0007807297,0.9904146,0.0004449039,0.005575541,0.00001727754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9548653,0.001268624,0.02786363,0.0002219361,0.0001493417,0.0001862875,0.0007402325,0.0002713273,0.01443339],"genre_scores_gemma":[0.9847358,0.001402198,0.008963411,0.000060656,0.00001335547,0.00008447249,0.0006674248,0.00004391788,0.004028741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001731606,"threshold_uncertainty_score":0.005792797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089852261441444,"score_gpt":0.2359264733633063,"score_spread":0.2250279507488919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}