{"id":"W2045379103","doi":"10.1080/07391102.2006.10507100","title":"Thermodynamics of Interactions of TAlPyP4 and AgTAlPyP4 Porphyrins with Poly(rA)poly(rU) and Poly(rI)poly(rC) Duplexes","year":2006,"lang":"en","type":"article","venue":"Journal of Biomolecular Structure and Dynamics","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"International Science and Technology Center","keywords":"Porphyrin; Chemistry; Intercalation (chemistry); Stacking; Circular dichroism; Nucleic acid; Polynucleotide; Crystallography; Ligand (biochemistry); Stereochemistry; Photochemistry; Organic chemistry; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007945422,0.0002857861,0.0004156139,0.0001237721,0.00007448294,0.00003540646,0.0001640022,0.0002246211,0.000007681401],"category_scores_gemma":[0.0000210585,0.0002279016,0.0001204118,0.0001298175,0.0004206281,0.00002281018,0.0001225061,0.0002104531,4.478198e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002021062,"about_ca_system_score_gemma":0.00008357112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001124368,"about_ca_topic_score_gemma":0.0001786736,"domain_scores_codex":[0.9987454,0.00003300286,0.0005101914,0.0002684387,0.0002201613,0.0002227679],"domain_scores_gemma":[0.9988058,0.00001825366,0.0006044706,0.0002662337,0.0001751326,0.0001300844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002920182,0.00007559729,0.01049132,0.0001317898,0.0002609421,0.00003763747,0.0000662255,0.000006699178,0.980051,0.0005405504,0.00002197382,0.008024286],"study_design_scores_gemma":[0.002704117,0.001423872,0.03303873,0.0002267627,0.000451101,0.003823862,0.0005796601,0.002015257,0.9526042,0.001680484,0.0008011152,0.0006508367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791579,0.008422104,0.01154428,0.0001365404,0.00008824106,0.00007793331,0.0001901636,0.000004383644,0.0003784193],"genre_scores_gemma":[0.9948028,0.0005281495,0.00425534,0.00005801546,0.000122691,7.158891e-7,0.00008358805,0.00003409165,0.0001145481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02744676,"threshold_uncertainty_score":0.9293559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001839825267269001,"score_gpt":0.1992349372974133,"score_spread":0.1973951120301443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}