{"id":"W2045394548","doi":"10.1074/jbc.m404749200","title":"Biochemical Characterization of WbpA, a UDP-N-acetyl-d-glucosamine 6-Dehydrogenase Involved in O-antigen Biosynthesis in Pseudomonas aeruginosa PAO1","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Institute for Biological Sciences","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of St Andrews; McMaster University; University of Guelph","keywords":"Chemistry; NAD+ kinase; Enzyme kinetics; Dehydrogenase; Pseudomonas putida; Stereochemistry; Enzyme; Biochemistry; Chromatography; Active site","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003507148,0.0002446027,0.0005068689,0.00009819035,0.00001822257,0.00001101116,0.0004011521,0.0008479922,0.00003239639],"category_scores_gemma":[0.0003192402,0.000195517,0.000192278,0.0002896766,0.000246617,0.00000649727,0.0001554771,0.0003019117,0.000001250884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005511685,"about_ca_system_score_gemma":0.000134319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000113606,"about_ca_topic_score_gemma":0.000007546473,"domain_scores_codex":[0.9982464,0.00005338623,0.0008958725,0.000336228,0.0001420396,0.0003260278],"domain_scores_gemma":[0.9989909,0.00001865915,0.0005005075,0.000259783,0.0001198275,0.000110335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004161266,0.0004325675,0.008589539,0.00003454102,0.0000364015,0.00003902496,0.00001546168,0.00001457999,0.9898459,0.000007770485,0.000007643129,0.0005603938],"study_design_scores_gemma":[0.001522208,0.0004282774,0.01025854,0.00009081095,0.000009830783,0.00008456784,0.0000470415,0.000005355337,0.9864341,0.0001119279,0.0007891733,0.0002181442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985729,0.0006308511,0.00009043646,0.0004283505,0.00007508961,0.0001158571,0.00003882284,0.000005921187,0.00004170709],"genre_scores_gemma":[0.9966383,0.002041932,0.0008706392,0.00007768469,0.0002143507,0.000005607271,0.000129508,0.00001457725,0.000007378442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003411822,"threshold_uncertainty_score":0.7972952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01212504540948521,"score_gpt":0.2226071101316754,"score_spread":0.2104820647221902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}