{"id":"W2045427549","doi":"10.1016/j.sbi.2003.10.012","title":"Sub-Ångstrom resolution enzyme X-ray structures: is seeing believing?","year":2003,"lang":"en","type":"review","venue":"Current Opinion in Structural Biology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Health Canada; National Institutes of Health","keywords":"Protein Data Bank (RCSB PDB); Crystallography; Protein Data Bank; Resolution (logic); Triosephosphate isomerase; Rubredoxin; Chemistry; Protein structure; Enzyme; Stereochemistry; Computer science; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004391519,0.001337489,0.003767631,0.00134042,0.0005293869,0.002591523,0.004193407,0.00417315,0.00279742],"category_scores_gemma":[0.004433445,0.0006449731,0.0006205837,0.00209099,0.002707545,0.005840924,0.0009310109,0.004702331,0.004384166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001320077,"about_ca_system_score_gemma":0.001797148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001488889,"about_ca_topic_score_gemma":0.002037392,"domain_scores_codex":[0.9993938,0.0001080231,0.00006894267,0.0001104292,0.0002667801,0.00005194244],"domain_scores_gemma":[0.9967781,0.001445406,0.0003398257,0.0001663958,0.001033037,0.0002371968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002201254,0.00006894656,0.0003449482,0.007923609,0.00009033912,0.0002948082,0.000150665,0.0003632292,0.003289045,0.01084215,0.07158607,0.9048262],"study_design_scores_gemma":[0.00005715332,0.0001184064,0.0006810191,0.002264604,0.0001196686,0.001808874,0.0002076633,0.000239547,0.001426386,0.009948329,0.9830784,0.00004998979],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001792949,0.9940142,0.0008841783,0.003127179,0.0009081666,0.000004422829,0.00001707441,0.00002451827,0.0008410045],"genre_scores_gemma":[0.0008963859,0.9959888,0.0008130472,0.001160006,0.0006023493,0.000006765401,0.0000463377,0.000004850708,0.0004814217],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004391519,"threshold_uncertainty_score":0.02322489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07168983362535117,"score_gpt":0.3743756454623524,"score_spread":0.3026858118370013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}