{"id":"W2045488160","doi":"10.1016/j.str.2011.09.023","title":"Structure of Hydrogenase Maturation Protein HypF with Reaction Intermediates Shows Two Active Sites","year":2011,"lang":"en","type":"article","venue":"Structure","topic":"Metalloenzymes and iron-sulfur proteins","field":"Energy","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Biotechnology Research Institute; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Active site; Nucleotide; Chemistry; Protein subunit; Binding site; Protein structure; Biochemistry; Stereochemistry; Hydrogenase; Crystallography; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009792052,0.0005477763,0.0003468104,0.0002370831,0.0005670933,0.0004869252,0.0005970604,0.00128976,0.002769592],"category_scores_gemma":[0.0002560042,0.0002986433,0.0004557258,0.0002794061,0.000371129,0.0006315886,0.0002253381,0.001345258,0.0006250452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007512945,"about_ca_system_score_gemma":0.00040052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003117537,"about_ca_topic_score_gemma":0.001448773,"domain_scores_codex":[0.9999287,0.000005211846,0.000002726512,0.00002634887,0.00001572476,0.00002125388],"domain_scores_gemma":[0.9997454,0.00005534043,0.00006266421,0.00002133507,0.00003002069,0.0000852147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001660423,0.0002524839,0.002960899,0.0001626978,0.00003635715,0.002435454,0.0002092814,0.001008586,0.9770992,0.002282793,0.002101547,0.009790225],"study_design_scores_gemma":[0.0001684643,0.0007554337,0.05610671,0.00003827124,0.0000578095,0.004352894,0.0004111682,0.01267386,0.904748,0.001923646,0.01867347,0.00009033916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836701,0.001499591,0.008049598,0.0008745346,0.0001021822,0.00004171298,0.0009257858,0.0004574754,0.004379085],"genre_scores_gemma":[0.9844428,0.000289795,0.007512239,0.0001454643,0.00002846188,0.00002737857,0.002562327,0.00005653394,0.004934955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003117537,"threshold_uncertainty_score":0.009265184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01223273607573428,"score_gpt":0.2121412955505061,"score_spread":0.1999085594747718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}