{"id":"W2045509448","doi":"10.1177/1933719107309647","title":"Opposite Effect of Phorbol Ester PMA on PTGS2 and PGDH mRNA Expression in Human Chorion Trophoblast Cells","year":2008,"lang":"en","type":"article","venue":"Reproductive Sciences","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Protein kinase C; p38 mitogen-activated protein kinases; Phorbol; Trophoblast; Protein kinase A; Kinase; Messenger RNA; Stimulation; MAPK/ERK pathway; Biology; Signal transduction; Downregulation and upregulation; Endocrinology; Molecular biology; Chemistry; Cell biology; Internal medicine; Biochemistry; Placenta; Fetus; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004218576,0.000131288,0.0001622277,0.00008667509,0.0001596476,0.00000966045,0.0001242301,0.00009537694,0.000002579179],"category_scores_gemma":[0.0000558453,0.00009118459,0.00004562037,0.0001707793,0.000452202,0.0000103188,0.0000728058,0.0001015518,0.000002821402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009133024,"about_ca_system_score_gemma":0.00002211649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001682122,"about_ca_topic_score_gemma":8.94025e-7,"domain_scores_codex":[0.9987422,0.0001549543,0.0001418229,0.0006195972,0.0001662452,0.0001751391],"domain_scores_gemma":[0.9995765,0.00002065686,0.00008291317,0.0002474571,0.00002596483,0.0000465247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001381881,0.00005313947,0.00647227,0.00001317148,0.000006815599,0.00001123986,0.0001475482,0.0001120094,0.9923335,0.000004433131,0.0001058936,0.0006017979],"study_design_scores_gemma":[0.0004172371,0.002604612,0.008923213,0.00005112651,0.00000554413,0.00003893982,0.00002213956,0.00001189968,0.9876968,0.00001166108,0.0001107907,0.0001060776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975924,0.001115907,0.000005748333,0.00003115121,0.0001223007,0.0002476299,0.000001654891,0.000005337771,0.0008778793],"genre_scores_gemma":[0.9992948,0.0002662101,0.00009505921,0.00001069067,0.0001147978,0.000009634966,0.000003497403,0.000007236996,0.0001980634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004636735,"threshold_uncertainty_score":0.37184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00865112658748654,"score_gpt":0.2574551759759989,"score_spread":0.2488040493885123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}