{"id":"W2045509448","doi":"10.1177/1933719107309647","title":"Opposite Effect of Phorbol Ester PMA on PTGS2 and PGDH mRNA Expression in Human Chorion Trophoblast Cells","year":2008,"lang":"en","type":"article","venue":"Reproductive Sciences","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Protein kinase C; p38 mitogen-activated protein kinases; Phorbol; Trophoblast; Protein kinase A; Kinase; Messenger RNA; Stimulation; MAPK/ERK pathway; Biology; Signal transduction; Downregulation and upregulation; Endocrinology; Molecular biology; Chemistry; Cell biology; Internal medicine; Biochemistry; Placenta; Fetus; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001515687,0.0002436732,0.0002336091,0.0002454495,0.0001901354,0.0002924256,0.00009795564,0.0002054127,0.0025807],"category_scores_gemma":[0.0001982577,0.0001984289,0.0002194046,0.000167995,0.0002789938,0.0002571371,0.0001755006,0.0004859714,0.0004301479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000223239,"about_ca_system_score_gemma":0.0003148853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0012911,"about_ca_topic_score_gemma":0.001187638,"domain_scores_codex":[0.9998648,0.00003032074,0.00001442502,0.00002879143,0.00002233311,0.00003939475],"domain_scores_gemma":[0.9998629,0.00006209336,0.000007639876,0.00002204583,0.00001357193,0.00003173673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007149162,0.00002111577,0.0002987428,0.00005017356,0.000003791449,0.0001824142,0.0000631094,0.0000168579,0.9973477,0.000147931,0.00004499781,0.001108223],"study_design_scores_gemma":[0.00003126782,0.0002387454,0.007485338,0.000004942,0.00001376384,0.0002403202,0.0001140554,0.000135326,0.9893349,0.00006154746,0.002335801,0.000003988384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883652,0.002740035,0.001693503,0.0002388544,0.0001624936,0.0000328229,0.0008174014,0.00006743819,0.005882285],"genre_scores_gemma":[0.9831482,0.001807963,0.001590592,0.0001238484,0.00006580562,0.00006285083,0.000989586,0.00001878007,0.01219244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0025807,"threshold_uncertainty_score":0.008633316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00865112658748654,"score_gpt":0.2574551759759989,"score_spread":0.2488040493885123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}