{"id":"W2045589622","doi":"10.1016/j.eururo.2014.06.045","title":"Efficacy of Enzalutamide Following Abiraterone Acetate in Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer Patients","year":2014,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Enzalutamide; Abiraterone acetate; Prostate cancer; Abiraterone; Oncology; Chemotherapy; Urology; Internal medicine; Cancer; Androgen deprivation therapy; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004763081,0.0003180065,0.001271775,0.0003128105,0.0002220947,0.0004617493,0.0003442514,0.0003079365,0.0008858222],"category_scores_gemma":[0.001493437,0.0001509498,0.0006469064,0.0003834093,0.0002665915,0.0003896066,0.0001777424,0.0009218828,0.000168265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006304787,"about_ca_system_score_gemma":0.0007659963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003409761,"about_ca_topic_score_gemma":0.01137076,"domain_scores_codex":[0.9997414,0.0001066678,0.00002758315,0.00003667097,0.000042447,0.00004534293],"domain_scores_gemma":[0.9994038,0.0001631187,0.0001525515,0.00003347085,0.00003243345,0.0002146518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5973222,0.005912226,0.1145879,0.0006455276,0.002157768,0.0007522292,0.0004436367,0.004786011,0.01307363,0.0002203968,0.001392487,0.2587059],"study_design_scores_gemma":[0.05288006,0.1828273,0.7414244,0.0002820692,0.004366705,0.001613728,0.0004199844,0.003997341,0.004994097,0.0006863142,0.006376467,0.0001315492],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928098,0.005435971,0.00005048425,0.0001900037,0.00005644415,0.00003710098,0.0001914307,0.00001653212,0.001212234],"genre_scores_gemma":[0.9975999,0.001437205,0.00006323556,0.00009507732,0.0000501419,0.0000136257,0.0002713731,0.00000310465,0.0004663512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003409761,"threshold_uncertainty_score":0.00677985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02039178408978887,"score_gpt":0.3027230015513336,"score_spread":0.2823312174615447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}