{"id":"W2045601151","doi":"10.4161/21688362.2014.970940","title":"Connecting metabolism to intestinal barrier function: The role of leptin","year":2014,"lang":"en","type":"article","venue":"Tissue Barriers","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Cell biology; Adherens junction; Tight junction; Paracellular transport; Actin cytoskeleton; Leptin; RHOA; Barrier function; Signal transduction; Biology; Intestinal epithelium; Actin remodeling; Cytoskeleton; Cell junction; Intestinal mucosa; Epithelium; Cell; Endocrinology; Internal medicine; Cadherin; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006095998,0.0004129565,0.0006669873,0.0004428645,0.0005046666,0.00200682,0.0005941786,0.002197843,0.001170551],"category_scores_gemma":[0.0007823868,0.0001078976,0.0002938456,0.0003573125,0.001945596,0.001755997,0.0009613685,0.002745859,0.000327758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007893994,"about_ca_system_score_gemma":0.0008601455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007374717,"about_ca_topic_score_gemma":0.001917718,"domain_scores_codex":[0.9996728,0.0001168406,0.00003402717,0.00006294606,0.00007138358,0.00004197897],"domain_scores_gemma":[0.9997845,0.00008849138,0.00003489728,0.000006082199,0.00005616444,0.00002979854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007173491,0.0001587757,0.003777856,0.009433878,0.0002681936,0.009369314,0.003105781,0.0009409649,0.07907781,0.1808958,0.1194266,0.5928277],"study_design_scores_gemma":[0.00003225215,0.0006380018,0.006382748,0.004388226,0.0001818846,0.007036336,0.00258889,0.0009149511,0.01269602,0.0606339,0.9044099,0.0000968927],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.006042896,0.9189843,0.002016551,0.05946416,0.009060089,0.00001216613,0.00002254178,0.00001798444,0.004379307],"genre_scores_gemma":[0.04686779,0.9058458,0.001329396,0.01725602,0.02124979,0.00002884976,0.00002057811,0.00001604604,0.007385718],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002197843,"threshold_uncertainty_score":0.00572753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01187675382601859,"score_gpt":0.2443266798820905,"score_spread":0.232449926056072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}