{"id":"W2045741487","doi":"10.1016/j.ijpharm.2008.07.015","title":"Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents","year":2008,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Laurentian University; NOSM University; Lakehead University","funders":"","keywords":"Acetylcysteine; Pharmacology; ARDS; Medicine; Bronchoalveolar lavage; Oxidative stress; Myeloperoxidase; Lung; Lipopolysaccharide; Lipid peroxidation; Immunology; Chemistry; Antioxidant; Internal medicine; Inflammation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004406892,0.0006845098,0.0007449949,0.0006617716,0.0002989703,0.0003697745,0.0005903856,0.0008898278,0.001410639],"category_scores_gemma":[0.0003195736,0.0002978469,0.0004313148,0.0002162428,0.000782263,0.0006957614,0.0002612205,0.001112954,0.0003685974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002867551,"about_ca_system_score_gemma":0.0005846947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007790431,"about_ca_topic_score_gemma":0.000808312,"domain_scores_codex":[0.9997796,0.00003971837,0.00002640113,0.00004329848,0.000036976,0.00007395529],"domain_scores_gemma":[0.9995413,0.00004984057,0.0001088108,0.00005734027,0.0000614142,0.0001814204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01775049,0.002010413,0.0004742204,0.0002522322,0.00009679102,0.0001752116,0.00007099166,0.0003960628,0.9717876,0.0002847055,0.0001861523,0.006515058],"study_design_scores_gemma":[0.0004316841,0.008591937,0.001398305,0.00001805918,0.00009565697,0.00012424,0.00004882843,0.0006509362,0.9879112,0.00009294232,0.0006209947,0.00001513718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962459,0.00156352,0.0008173684,0.0001812234,0.00008742457,0.00005074891,0.0002475246,0.0001147296,0.0006915765],"genre_scores_gemma":[0.9958392,0.0009391536,0.0006967951,0.00007789284,0.00003537396,0.00005263918,0.0002991656,0.00001679391,0.002042942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001410639,"threshold_uncertainty_score":0.004719019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.019408507407609,"score_gpt":0.334590474651524,"score_spread":0.315181967243915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}