{"id":"W2045743613","doi":"10.1016/j.transproceed.2004.01.055","title":"Therapeutic monitoring of cyclosporine in kidney transplantation: the Halifax experience","year":2004,"lang":"en","type":"article","venue":"Transplantation Proceedings","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Dosing; Therapeutic drug monitoring; Immunosuppression; Tolerability; Medicine; Nephrotoxicity; Transplantation; Pharmacology; Pharmacokinetics; Kidney transplantation; Area under the curve; Intensive care medicine; Urology; Internal medicine; Kidney; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001212934,0.0001903086,0.0002592783,0.0001525477,0.00007708369,0.00001925284,0.0001150701,0.00007121576,0.0000361582],"category_scores_gemma":[0.000006828182,0.0001330788,0.00009729232,0.0004553707,0.00008782804,0.000267862,0.000001954207,0.0001567636,0.000009766138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006023653,"about_ca_system_score_gemma":0.00007987011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001866132,"about_ca_topic_score_gemma":0.000007984698,"domain_scores_codex":[0.9986603,0.000007863054,0.000467038,0.0002454198,0.0003950312,0.0002243959],"domain_scores_gemma":[0.9995373,0.000039498,0.0001151968,0.00009140995,0.0001046811,0.0001118995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001579968,0.0003365479,0.9027765,0.002579501,0.0001203892,0.0001769067,0.03641431,0.0001515504,0.0473552,0.007659467,0.000001339843,0.0008482999],"study_design_scores_gemma":[0.006794191,0.0001987727,0.7634454,0.00183111,0.0002638948,0.0004969439,0.001162575,0.000009981691,0.2249908,0.0006145804,0.00003505628,0.0001567051],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953515,0.0001258688,0.0008220949,0.001002362,0.0001241343,0.0005240262,0.00003462923,0.00005509953,0.001960269],"genre_scores_gemma":[0.9955785,0.002474411,0.001414365,0.0002329464,0.0000486496,0.00008194831,0.00006241231,0.00002102688,0.0000857116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1776356,"threshold_uncertainty_score":0.5426795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0278772199288719,"score_gpt":0.3067006766200265,"score_spread":0.2788234566911546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}