{"id":"W2045751955","doi":"10.1001/jama.299.13.1598","title":"Newly Approved Does Not Always Mean New and Improved","year":2008,"lang":"en","type":"article","venue":"JAMA","topic":"Pharmaceutical industry and healthcare","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Otorhinolaryngology; Family medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007845582,0.0005860131,0.0009100963,0.001648341,0.002003482,0.009624753,0.001369518,0.004183458,0.2705487],"category_scores_gemma":[0.03580599,0.0005512972,0.001101848,0.001621477,0.002379271,0.01189307,0.002589794,0.007428707,0.180015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00152329,"about_ca_system_score_gemma":0.003177388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001270944,"about_ca_topic_score_gemma":0.004179962,"domain_scores_codex":[0.993059,0.001375769,0.0005617402,0.0006748683,0.003760713,0.0005678147],"domain_scores_gemma":[0.9738166,0.003974349,0.00172958,0.005006129,0.009372455,0.006100905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003387023,0.00007501186,0.0004533516,0.0001606735,0.00001446647,0.00006879104,0.0000816118,0.00003055954,0.000308202,0.007806899,0.9028593,0.08810729],"study_design_scores_gemma":[0.000009101016,0.00003945697,0.0004322009,0.00009390544,0.000005695112,0.0001574094,0.00005299549,0.00001659768,0.0001178091,0.001174086,0.9978897,0.00001109918],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.003083557,0.01956912,0.00322866,0.1991253,0.08077703,0.0001759734,0.001376036,0.003790771,0.6888735],"genre_scores_gemma":[0.02995924,0.01916185,0.006805948,0.1154529,0.03007296,0.0002104821,0.001556309,0.002548971,0.7942314],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.2705487,"threshold_uncertainty_score":0.9050756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3528179821470994,"score_gpt":0.4868205929251561,"score_spread":0.1340026107780567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}