{"id":"W2045752787","doi":"10.1210/endo.141.11.7765","title":"Estrogen Deficiency, Obesity, and Skeletal Abnormalities in Follicle-Stimulating Hormone Receptor Knockout (FORKO) Female Mice**This investigation was supported in part by the Canadian Institutes of Health Research.","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":210,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Shriners Hospitals for Children","keywords":"Endocrinology; Internal medicine; Estrogen; Knockout mouse; Follicle-stimulating hormone; Obesity; Estrogen receptor; Medicine; Hormone; Biology; Receptor; Luteinizing hormone; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006627776,0.000147477,0.0002275103,0.000170611,0.0002442763,0.00001804668,0.0001907518,0.0001893547,0.00002994709],"category_scores_gemma":[0.0001298037,0.0001281528,0.00003803517,0.0002766205,0.0005299241,0.00001302144,0.00007571958,0.0003696853,0.00001096142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000837223,"about_ca_system_score_gemma":0.000453017,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.08082724,"about_ca_topic_score_gemma":0.04148162,"domain_scores_codex":[0.9979395,0.000488108,0.0004071719,0.0003205158,0.0001408981,0.0007037894],"domain_scores_gemma":[0.9994667,0.00006804632,0.00007805384,0.0002100746,0.00004454686,0.000132591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003016141,0.0004193075,0.6116486,0.0001969812,0.0001671101,0.00009974784,0.006016899,0.0009091051,0.3063869,0.004604092,0.01467214,0.05457748],"study_design_scores_gemma":[0.01145008,0.009056008,0.2081892,0.0003802967,0.00007297389,0.0008386372,0.004168313,0.001260781,0.5773555,0.001556723,0.1836647,0.002006768],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853188,0.01204213,0.000001000667,0.001094173,0.00005407275,0.0003669812,0.00002953515,0.000008141319,0.001085194],"genre_scores_gemma":[0.9975272,0.00153638,0.00009806077,0.0001605991,0.00003757518,0.00003575456,0.0002091812,0.00001401917,0.0003811716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4034595,"threshold_uncertainty_score":0.9760088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03145279498669584,"score_gpt":0.2905411862855282,"score_spread":0.2590883912988323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}