{"id":"W2045752787","doi":"10.1210/endo.141.11.7765","title":"Estrogen Deficiency, Obesity, and Skeletal Abnormalities in Follicle-Stimulating Hormone Receptor Knockout (FORKO) Female Mice**This investigation was supported in part by the Canadian Institutes of Health Research.","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":210,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Shriners Hospitals for Children","keywords":"Endocrinology; Internal medicine; Estrogen; Knockout mouse; Follicle-stimulating hormone; Obesity; Estrogen receptor; Medicine; Hormone; Biology; Receptor; Luteinizing hormone; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003101619,0.0009686194,0.0003454947,0.001514947,0.0004715062,0.0003306044,0.0003114046,0.0006819512,0.00372163],"category_scores_gemma":[0.0001811531,0.0005493606,0.0003791544,0.0003328504,0.0005288732,0.0002796209,0.0003208508,0.0008817755,0.0007473486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003502415,"about_ca_system_score_gemma":0.0002426119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001066004,"about_ca_topic_score_gemma":0.00233235,"domain_scores_codex":[0.9997233,0.0000323789,0.00003646337,0.00008558411,0.00006704076,0.00005521164],"domain_scores_gemma":[0.9995609,0.00004976949,0.0001610356,0.00003446347,0.00003462787,0.0001592498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003494075,0.0001075679,0.001204902,0.00003802295,0.00001573832,0.000415684,0.00003503947,0.00004151127,0.9955276,0.0002562378,0.0001512093,0.001857083],"study_design_scores_gemma":[0.0005097185,0.003033448,0.1106007,0.0001272428,0.0002125228,0.01476817,0.0003518656,0.001687006,0.8513421,0.0005718349,0.01672538,0.0000700588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895672,0.001197545,0.00344264,0.000357507,0.00005524241,0.00008203556,0.002734331,0.0002271733,0.002336458],"genre_scores_gemma":[0.9599507,0.002710559,0.007837813,0.0002757265,0.00006310963,0.0002665586,0.004113227,0.0003125854,0.02446977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00372163,"threshold_uncertainty_score":0.0124501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03145279498669584,"score_gpt":0.2905411862855282,"score_spread":0.2590883912988323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}