{"id":"W2045757118","doi":"10.1021/ac000318+","title":"Studies of Protein−DNA Interactions by Capillary Electrophoresis/Laser-Induced Fluorescence Polarization","year":2000,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Microfluidic and Capillary Electrophoresis Applications","field":"Engineering","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fluorescence anisotropy; Chemistry; Capillary electrophoresis; Electrophoresis; Fluorescence; DNA; Oligonucleotide; Laser-induced fluorescence; Electrophoretic mobility shift assay; Binding constant; Biophysics; Analytical Chemistry (journal); Chromatography; Binding site; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005143468,0.0001850071,0.0002466111,0.00002604901,0.00007906072,0.00001487504,0.0001760946,0.0001006827,0.0009288757],"category_scores_gemma":[0.00003387003,0.0001870393,0.00008714879,0.0003545634,0.00008318156,0.00006936476,0.00001564615,0.0002237716,0.00004668665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001012306,"about_ca_system_score_gemma":0.00003189105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009420281,"about_ca_topic_score_gemma":5.394769e-7,"domain_scores_codex":[0.9989624,0.00001335675,0.0003388157,0.0002299458,0.0001766622,0.0002788441],"domain_scores_gemma":[0.9994354,0.00003536725,0.00003424841,0.0003082958,0.00008509942,0.0001015378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001172752,0.00004725262,0.00002406079,0.00009021467,0.0001229439,0.00000170702,0.00002608375,0.000004678255,0.9693467,0.00005431808,0.0285334,0.001736917],"study_design_scores_gemma":[0.0001132321,0.000020476,0.00002591752,0.00003415365,0.00005700224,0.000008026077,0.00004584866,0.001911627,0.983933,0.0001120166,0.01355738,0.0001813403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893185,0.006341262,0.00005388561,0.0001397119,0.00001126559,0.0001344468,0.0000227272,0.0001223154,0.003855846],"genre_scores_gemma":[0.9876627,0.009759655,0.00003554585,0.00002401971,0.00006052219,0.00004238769,0.00008448091,0.00002892406,0.002301757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01497602,"threshold_uncertainty_score":0.9999844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009296494518406934,"score_gpt":0.2357426986223261,"score_spread":0.2264462041039192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}