{"id":"W2045759734","doi":"10.1038/labinvest.3780362","title":"Focal Adhesion Kinase Is a Key Mediator of Human Trophoblast Development","year":2001,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Mount Sinai Hospital; Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Focal adhesion; Cytotrophoblast; Paxillin; Trophoblast; Biology; Cell biology; PTK2; Extracellular matrix; Integrin; Matrigel; Cell adhesion; MMP2; Signal transduction; Cell; Kinase; Placenta; Protein kinase A; Downregulation and upregulation; Biochemistry; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003598701,0.0002089359,0.0001575829,0.0008636963,0.0003728246,0.0004995093,0.0002128636,0.0002466132,0.001736493],"category_scores_gemma":[0.0007506211,0.0001216582,0.00009258485,0.0004758394,0.0002928427,0.0003353473,0.0002923768,0.000356172,0.000228255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004606438,"about_ca_system_score_gemma":0.0004318706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001649675,"about_ca_topic_score_gemma":0.001116227,"domain_scores_codex":[0.9998415,0.00005897381,0.00001243526,0.00002424208,0.00003830611,0.00002469033],"domain_scores_gemma":[0.9998001,0.0000613293,0.00005280351,0.00001519525,0.0000280072,0.00004248707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004544534,0.0004579204,0.1553149,0.0008845096,0.0002445686,0.005062905,0.001524363,0.0002003963,0.6876233,0.007316608,0.001613362,0.1352127],"study_design_scores_gemma":[0.000115769,0.001624824,0.6770679,0.0001146497,0.0003257736,0.01216355,0.001515076,0.0004509812,0.2727534,0.001952914,0.03187983,0.00003527443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9519563,0.03543764,0.001440626,0.0006310834,0.00005854772,0.00004325882,0.0002506368,0.00002112596,0.01016089],"genre_scores_gemma":[0.9881242,0.008013322,0.0008102802,0.00005286661,0.00004187254,0.00002382689,0.0001653418,0.000002776216,0.002765707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001736493,"threshold_uncertainty_score":0.005809128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02787581477567682,"score_gpt":0.2677565572477428,"score_spread":0.239880742472066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}