{"id":"W2045789879","doi":"10.1016/j.ijrobp.2004.02.022","title":"Report of a multicenter Canadian phase III randomized trial of 3 months vs. 8 months neoadjuvant androgen deprivation before standard-dose radiotherapy for clinically localized prostate cancer","year":2004,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; Island Health; Northeast Cancer Centre; Ottawa Regional Cancer Foundation; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Flutamide; Urology; Prostate cancer; Radiation therapy; Goserelin; Prostate; Prostate-specific antigen; Androgen deprivation therapy; Hormonal therapy; Stage (stratigraphy); Antiandrogen; Clinical endpoint; Randomized controlled trial; Cancer; Internal medicine; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00138434,0.0002393836,0.00152859,0.0002342526,0.00005334191,0.00001425867,0.0002088223,0.0002293562,0.00003898803],"category_scores_gemma":[0.0007844652,0.0001858028,0.0006346668,0.0001305389,0.0002936561,0.0001859634,0.00001882778,0.0002266645,5.043184e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001981381,"about_ca_system_score_gemma":0.003674389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003556805,"about_ca_topic_score_gemma":0.001040095,"domain_scores_codex":[0.9966381,0.0001742067,0.002283137,0.0002794354,0.0003627014,0.0002624104],"domain_scores_gemma":[0.9940577,0.0004360661,0.003170991,0.0002011297,0.001893666,0.0002404079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7770084,0.001962974,0.04794995,0.00003133369,0.003577888,0.0001499426,0.001499136,0.00178897,0.0006788322,0.001063071,0.0002789923,0.1640106],"study_design_scores_gemma":[0.9659505,0.009490627,0.001041141,0.0002529403,0.0006916542,0.00008012928,0.00005094049,0.001895714,0.006521191,0.003854005,0.01001926,0.0001519283],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680031,0.001470229,0.01628504,0.007355245,0.002170376,0.003861876,0.0007919119,0.0000156841,0.00004654492],"genre_scores_gemma":[0.9848943,0.004324783,0.008279766,0.0007369665,0.001016597,0.0003153267,0.0003769147,0.00003692893,0.00001842408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1889421,"threshold_uncertainty_score":0.7576817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01860458289646351,"score_gpt":0.3738432116014494,"score_spread":0.3552386287049859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}