{"id":"W2045875106","doi":"10.1186/gb-2008-9-4-216","title":"The AAA+ superfamily of functionally diverse proteins","year":2008,"lang":"en","type":"review","venue":"Genome Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":298,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"SUPERFAMILY; Computational biology; Biology; Structural motif; Evolutionary biology; Genetics; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007597835,0.001814478,0.00227603,0.001580148,0.0005624016,0.001847899,0.002072694,0.001728443,0.002495944],"category_scores_gemma":[0.0004482867,0.0005425432,0.0004854871,0.0031478,0.001371867,0.002324142,0.001154071,0.002834436,0.004783984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001008743,"about_ca_system_score_gemma":0.000902675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000579099,"about_ca_topic_score_gemma":0.0008040403,"domain_scores_codex":[0.999775,0.00002317597,0.00002601094,0.00005929856,0.00009071126,0.00002591758],"domain_scores_gemma":[0.9997754,0.00006335231,0.00004397947,0.00001380222,0.00006212909,0.00004140356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001290896,0.00004432576,0.0001542994,0.004765029,0.0000585374,0.0002053376,0.00003809774,0.000353889,0.01064616,0.00878361,0.04330191,0.9315198],"study_design_scores_gemma":[0.00001581733,0.00002786983,0.0003014716,0.0003168417,0.00003663692,0.0009346154,0.00002578317,0.0000779131,0.001244536,0.002954006,0.9940514,0.00001304732],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004530814,0.9922117,0.002357534,0.0007050628,0.001024985,0.00001099322,0.00007538764,0.00006818882,0.003093143],"genre_scores_gemma":[0.001906927,0.991448,0.002017137,0.0006596148,0.0006641346,0.00002342345,0.0002552824,0.000009090912,0.003016382],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002495944,"threshold_uncertainty_score":0.008349776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03573508251985451,"score_gpt":0.2876520866970347,"score_spread":0.2519170041771802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}