{"id":"W2045959483","doi":"10.1006/bbrc.2001.4312","title":"Isolation of Endothelial Cells from Brain, Lung, and Kidney: Expression of the Multidrug Resistance P-Glycoprotein Isoforms","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Molecular biology; P-glycoprotein; Astrocyte; Glial fibrillary acidic protein; Biology; Western blot; Blot; Gene isoform; Endothelial stem cell; Kidney; Enos; Nitric oxide synthase; Gene; Chemistry; Nitric oxide; Biochemistry; Multiple drug resistance; Immunohistochemistry; In vitro; Immunology; Endocrinology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002481296,0.00009769212,0.0002191193,0.00004820548,0.0001866006,0.000009478774,0.0003392947,0.0001040816,0.00001983593],"category_scores_gemma":[0.0002545723,0.00005903098,0.00007832236,0.0003066314,0.0009909751,0.00004920791,0.0002219248,0.0003482344,0.000001194116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000207319,"about_ca_system_score_gemma":0.00008086916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001451932,"about_ca_topic_score_gemma":0.0000177666,"domain_scores_codex":[0.9988135,0.000102284,0.0002676812,0.0002018429,0.0004295234,0.0001852424],"domain_scores_gemma":[0.998353,0.0003478625,0.00008138624,0.0008428219,0.0002057691,0.000169168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003537464,0.0002931551,0.0007107375,0.0001050508,0.00001396428,4.987542e-7,0.0002051885,2.598743e-8,0.9958984,0.000984358,0.001035829,0.0003991002],"study_design_scores_gemma":[0.0007715232,0.0000535798,0.006975963,0.0005226377,0.00002394525,6.203148e-7,0.0001140157,0.0003699365,0.9842348,0.001603375,0.005260287,0.00006939551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896838,0.0009166941,0.0003562668,0.00776195,0.00001822171,0.0004848688,0.000194891,0.000013281,0.0005700348],"genre_scores_gemma":[0.9922127,0.001293897,0.005470417,0.00006745153,0.00004786332,0.0000278979,0.00004541237,0.00001002718,0.000824305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01166362,"threshold_uncertainty_score":0.3651289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02952210566315412,"score_gpt":0.3186916111148083,"score_spread":0.2891695054516542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}