{"id":"W2045970224","doi":"10.1002/chin.200333189","title":"Peptide Heterocycle Conjugates: A Diverted Edman Degradation Protocol for the Synthesis of N-Terminal 2-Iminohydantoins.","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Edman degradation; Terminal (telecommunication); Conjugate; Protocol (science); Degradation (telecommunications); Peptide; Combinatorial chemistry; Stereochemistry; Biochemistry; Peptide sequence; Computer network; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004086025,0.000551552,0.0003004782,0.0003024066,0.000334097,0.0002422349,0.0004173408,0.0003923873,0.00329726],"category_scores_gemma":[0.0002765281,0.0003301282,0.0002291472,0.0003503516,0.0002381515,0.0003109189,0.000264355,0.0009956985,0.001865515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000309711,"about_ca_system_score_gemma":0.0005422336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000342026,"about_ca_topic_score_gemma":0.001305428,"domain_scores_codex":[0.9997503,0.00005269071,0.00001993765,0.00005701312,0.00007523163,0.00004493057],"domain_scores_gemma":[0.9998467,0.00003458621,0.00002790228,0.00004070652,0.00002552164,0.00002461058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008402846,0.00002298019,0.00003086295,0.00007100646,0.000006788714,0.000103895,0.0000367326,0.0001299205,0.993331,0.0003717513,0.0002888854,0.005522206],"study_design_scores_gemma":[0.00001648829,0.0001176331,0.0002957866,0.000004619494,0.00000791591,0.0002728292,0.000006462595,0.0002274082,0.9912018,0.00007432768,0.007767812,0.000006905894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4790266,0.006176567,0.4851526,0.0003667595,0.0002604539,0.001468198,0.003615736,0.001665273,0.02226796],"genre_scores_gemma":[0.7077077,0.006671111,0.2439733,0.0002960574,0.000069177,0.001159338,0.006111192,0.0006016897,0.03341048],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.00329726,"threshold_uncertainty_score":0.01103044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01910601922643739,"score_gpt":0.2723668620527031,"score_spread":0.2532608428262657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}