{"id":"W2045985937","doi":"10.1242/dev.00893","title":"Mouse embryonic chimeras: tools for studying mammalian development","year":2003,"lang":"en","type":"review","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":203,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Embryonic stem cell; Chimera (genetics); Gene targeting; Cell biology; Mutant; Lineage (genetic); Phenotype; Genetics; Gene; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009244676,0.0007618582,0.001153089,0.0002184407,0.0003442959,0.0001656853,0.0007756334,0.0005270774,0.00004844593],"category_scores_gemma":[0.0001056779,0.0006842997,0.0003643736,0.0002059134,0.00004379202,0.000007398465,0.0004577984,0.0002823665,0.0002775697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003638412,"about_ca_system_score_gemma":0.003027794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.265525e-7,"about_ca_topic_score_gemma":0.000012264,"domain_scores_codex":[0.9962369,0.0001794501,0.0009698073,0.001143096,0.0004930774,0.0009776937],"domain_scores_gemma":[0.9985372,0.00005815859,0.0003208425,0.0006674558,0.0001588905,0.0002573846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001415586,0.0001294022,0.000004773452,0.00669817,0.0006765869,0.000009060768,0.00006354816,0.0000014467,0.0002632093,0.00001113003,0.003825861,0.9883026],"study_design_scores_gemma":[0.0004270248,0.0000636007,0.000008645813,0.001054225,0.00008111248,0.0000254964,0.00002909362,2.918167e-7,0.005995091,7.936478e-7,0.9914662,0.0008484504],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005729676,0.9938542,0.001281339,0.0000105092,0.0003306467,0.003117047,0.00003919702,0.00003076961,0.0007633214],"genre_scores_gemma":[0.00001307795,0.9475533,0.02083613,0.00008229278,0.0001533338,0.002429313,0.002737506,0.0001824576,0.02601258],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9876403,"threshold_uncertainty_score":0.9995608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0983050449788321,"score_gpt":0.3451304258259884,"score_spread":0.2468253808471563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}