{"id":"W2045985937","doi":"10.1242/dev.00893","title":"Mouse embryonic chimeras: tools for studying mammalian development","year":2003,"lang":"en","type":"review","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":203,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Embryonic stem cell; Chimera (genetics); Gene targeting; Cell biology; Mutant; Lineage (genetic); Phenotype; Genetics; Gene; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001343245,0.001576154,0.001663367,0.002245815,0.0003695149,0.001104361,0.002433788,0.001547665,0.004431735],"category_scores_gemma":[0.0005765961,0.0004841513,0.000430779,0.001930918,0.001056467,0.001368348,0.0009204241,0.003222408,0.006179513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009407852,"about_ca_system_score_gemma":0.0007396829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008515948,"about_ca_topic_score_gemma":0.0009801558,"domain_scores_codex":[0.9995351,0.00006333055,0.00004487273,0.00007273956,0.0002470105,0.0000369113],"domain_scores_gemma":[0.9996137,0.0001231383,0.00007323016,0.0000336628,0.00008643371,0.00006979013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001042551,0.00009631694,0.0002164064,0.007128485,0.00008341143,0.0005886673,0.00008151278,0.0005029797,0.03952015,0.01949721,0.0658126,0.866368],"study_design_scores_gemma":[0.00001729175,0.00003020175,0.0002614134,0.0004328996,0.00003776314,0.00152112,0.00001724542,0.00005323791,0.004974418,0.001685831,0.9909559,0.00001272176],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004774735,0.982338,0.008688198,0.0005112016,0.0007333416,0.00005801046,0.0001720272,0.0002987078,0.006723122],"genre_scores_gemma":[0.002081406,0.9844576,0.006873053,0.0004733437,0.0002024384,0.00009812087,0.0004065659,0.0000439195,0.005363592],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004431735,"threshold_uncertainty_score":0.01482558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0983050449788321,"score_gpt":0.3451304258259884,"score_spread":0.2468253808471563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}