{"id":"W2046036733","doi":"10.1021/bi052342t","title":"Role of Arginine Residues in the Active Site of the Membrane-Bound Lytic Transglycosylase B from <i>Pseudomonas aeruginosa</i>","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Peptidoglycan; Active site; Chemistry; Biochemistry; Enzyme kinetics; Binding site; Lytic cycle; Residue (chemistry); Alanine; Dipeptide; Stereochemistry; Glycosidic bond; Ligand (biochemistry); Peptide; Enzyme; Amino acid; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001360648,0.0002924822,0.0002800542,0.00005573133,0.0001120867,0.0002845806,0.0002984446,0.0003731089,0.0008342444],"category_scores_gemma":[0.0002628589,0.0001108656,0.0001859965,0.00005787408,0.0002435208,0.0001928186,0.0001419837,0.0003558892,0.000639985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002238183,"about_ca_system_score_gemma":0.0001513568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006065068,"about_ca_topic_score_gemma":0.0003400208,"domain_scores_codex":[0.9998769,0.0000310173,0.0000106418,0.00003177842,0.00002979484,0.00001988975],"domain_scores_gemma":[0.9998229,0.00004050767,0.00006438101,0.00001598306,0.00001494994,0.00004134555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002420243,0.00002425591,0.0006621281,0.00003395951,0.000005073262,0.000137374,0.00002279603,0.0002174112,0.9971952,0.0001263334,0.00001562229,0.001317684],"study_design_scores_gemma":[0.00002462853,0.0003021667,0.005695066,0.000009609242,0.00001812912,0.0006872474,0.0000707397,0.001886889,0.9898615,0.00006912725,0.001362452,0.00001237521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972791,0.0003148216,0.001954528,0.0000465927,0.000008233925,0.000005747729,0.00004601668,0.00003376797,0.0003112147],"genre_scores_gemma":[0.9979328,0.0001125476,0.00146041,0.00001509739,0.000002847906,0.000002892053,0.00009457711,0.0000129044,0.0003659111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008342444,"threshold_uncertainty_score":0.002790868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005384533916288957,"score_gpt":0.2271414789918426,"score_spread":0.2217569450755536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}