{"id":"W2046079073","doi":"10.1038/gene.2011.89","title":"Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes","year":2012,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hôpital Saint-Luc; University of Calgary; Université de Montréal; University of Alberta; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Toronto Western Hospital","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American Gastroenterological Association; Canadian Institutes of Health Research; Canada Research Chairs; Health Canada; National Institutes of Health","keywords":"Biology; Single-nucleotide polymorphism; Locus (genetics); Genetics; SNP; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002731515,0.0004487453,0.0003665055,0.0005442286,0.0004155835,0.0003135952,0.0001878449,0.0006629846,0.005645082],"category_scores_gemma":[0.001203719,0.0001939532,0.0005130747,0.0006538146,0.0003844416,0.0001670402,0.0002301674,0.0005178511,0.0002661422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001999723,"about_ca_system_score_gemma":0.000208504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001865821,"about_ca_topic_score_gemma":0.001945213,"domain_scores_codex":[0.9997048,0.00007917521,0.00003200731,0.00007374129,0.00004552993,0.00006472132],"domain_scores_gemma":[0.9989551,0.0003183986,0.0003647823,0.00007637603,0.00008117505,0.0002041204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002619546,0.00008216225,0.9689099,0.00006451425,0.0003465295,0.002399915,0.0001154271,0.0002233184,0.02077547,0.000207508,0.0003294714,0.003926327],"study_design_scores_gemma":[0.00003932331,0.0001841993,0.9923702,0.000009118175,0.0001404385,0.005117614,0.00008032397,0.0005669722,0.0009979828,0.0001942033,0.0002913179,0.000008144572],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986429,0.000287071,0.0001658914,0.000101248,0.00001627872,0.000004007306,0.0001879669,0.000008113539,0.0005865055],"genre_scores_gemma":[0.9995804,0.00003654303,0.00008365157,0.00001472768,0.0000111189,0.000001775629,0.00006191306,0.000002038251,0.00020782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005645082,"threshold_uncertainty_score":0.01888472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433636467329138,"score_gpt":0.2259294008532352,"score_spread":0.2115930361799438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}