{"id":"W2046079073","doi":"10.1038/gene.2011.89","title":"Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes","year":2012,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hôpital Saint-Luc; University of Calgary; Université de Montréal; University of Alberta; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Toronto Western Hospital","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American Gastroenterological Association; Canadian Institutes of Health Research; Canada Research Chairs; Health Canada; National Institutes of Health","keywords":"Biology; Single-nucleotide polymorphism; Locus (genetics); Genetics; SNP; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007887579,0.0001306154,0.0002715132,0.00006294887,0.0001622808,0.00001820664,0.0000913565,0.00008417189,0.00003005764],"category_scores_gemma":[0.0000437764,0.00008523274,0.00004719022,0.0001560245,0.00009601506,0.0002204798,0.00009776054,0.0001946432,0.000001612751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005991444,"about_ca_system_score_gemma":0.00007515074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001474846,"about_ca_topic_score_gemma":0.00001706642,"domain_scores_codex":[0.9990187,0.0002473012,0.0002099459,0.0001047249,0.0001855149,0.0002337567],"domain_scores_gemma":[0.9992062,0.0001620508,0.0001329082,0.0003569953,0.00007496456,0.00006687306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001977373,0.0004081909,0.9584527,0.0001689512,0.0001460475,0.000001297549,0.001500967,4.650507e-7,0.01907265,0.00003786715,0.00007792171,0.01993522],"study_design_scores_gemma":[0.001093837,0.0002375656,0.994709,0.00006097573,0.0002198513,0.00002166268,0.001598345,0.00002074308,0.0009694588,0.00003398768,0.0009288686,0.0001056833],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9750958,0.02376845,0.000009244479,0.000236711,0.00005968745,0.0002739682,0.00001871313,0.00000986455,0.000527559],"genre_scores_gemma":[0.994142,0.005216916,0.0001473328,0.0002968517,0.00006122894,0.00001182566,0.00003453765,0.00001168993,0.0000775986],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03625634,"threshold_uncertainty_score":0.347569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433636467329138,"score_gpt":0.2259294008532352,"score_spread":0.2115930361799438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}