{"id":"W2046079214","doi":"10.1073/pnas.97.8.4374","title":"NADPH oxidase is an O 2 sensor in airway chemoreceptors: Evidence from K + current modulation in wild-type and oxidase-deficient mice","year":2000,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; McMaster University; University of Toronto","funders":"National Heart, Lung, and Blood Institute; Medical Research Council; National Institutes of Health; Medical Research Council Canada","keywords":"NADPH oxidase; Oxidase test; Molecular biology; Cytochrome c oxidase; Chemistry; Patch clamp; Biology; Reactive oxygen species; Biochemistry; Biophysics; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00122754,0.0001857823,0.000221974,0.000401489,0.0002248586,0.0001051297,0.0008418424,0.0000930164,0.00003954058],"category_scores_gemma":[0.001651414,0.0001451622,0.00004905686,0.002496454,0.00100435,0.00192517,0.0001111783,0.0003074589,0.000007567229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007517627,"about_ca_system_score_gemma":0.00006879511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002801503,"about_ca_topic_score_gemma":8.585866e-7,"domain_scores_codex":[0.9966249,0.00005275747,0.0005581128,0.0007933019,0.001669844,0.0003010334],"domain_scores_gemma":[0.9990859,0.0002933351,0.000324174,0.00002831555,0.0001700536,0.0000982267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004763624,0.0001354816,0.005429862,0.00002219159,5.127993e-7,4.838675e-8,0.0009725045,0.00327864,0.9801101,0.0004146318,0.00006673577,0.009521666],"study_design_scores_gemma":[0.0002748659,0.00008149057,0.03076402,0.0002187379,0.000003349918,0.000005688796,0.0001360156,0.08868758,0.8776591,0.001939791,0.0000784773,0.0001508585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966028,0.0001013546,8.457412e-7,0.002707305,0.00003383697,0.0003309905,0.000018752,0.00001892205,0.0001852168],"genre_scores_gemma":[0.9984969,0.0002691502,0.0002047644,0.0009410213,0.00004913825,0.00001097028,1.989799e-7,0.000007221398,0.00002059409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.102451,"threshold_uncertainty_score":0.5919543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06534828383591625,"score_gpt":0.3092502496048357,"score_spread":0.2439019657689195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}