{"id":"W2046097935","doi":"10.1002/hup.994","title":"St. John's wort and Kava in treating major depressive disorder with comorbid anxiety: a randomised double‐blind placebo‐controlled pilot trial","year":2008,"lang":"en","type":"article","venue":"Human Psychopharmacology Clinical and Experimental","topic":"Natural Compound Pharmacology Studies","field":"Agricultural and Biological Sciences","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Placebo; Kava; Anxiety; Major depressive disorder; Beck Anxiety Inventory; Randomized controlled trial; Depression (economics); Antidepressant; Psychiatry; Double blind; Crossover study; Medicine; Hypericum; Psychology; Beck Depression Inventory; Internal medicine; Traditional medicine; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002594841,0.001276306,0.003496244,0.0007802229,0.0005869293,0.0009059903,0.0009783463,0.002633912,0.007657279],"category_scores_gemma":[0.003157489,0.0008625375,0.001977602,0.0006515706,0.001449319,0.001007158,0.0004772011,0.00157781,0.0007595667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005679338,"about_ca_system_score_gemma":0.001265306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001073184,"about_ca_topic_score_gemma":0.002196747,"domain_scores_codex":[0.9986787,0.0007685047,0.0001637449,0.0001489733,0.0001177306,0.0001223105],"domain_scores_gemma":[0.9986437,0.0005958003,0.0003039361,0.00008945518,0.00009496409,0.0002720737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9676672,0.006337841,0.0002413603,0.003173168,0.001021157,0.00005993655,0.00007278855,0.0001228292,0.002756288,0.00009293873,0.0003433178,0.01811116],"study_design_scores_gemma":[0.9656105,0.03325758,0.0003894937,0.00004435883,0.0002492498,0.00001754713,0.00001089858,0.00007307984,0.0001243086,0.0000276267,0.0001896368,0.000005713633],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.965179,0.01704863,0.001038985,0.0009805618,0.001062539,0.01224348,0.0006942421,0.0001483296,0.001604264],"genre_scores_gemma":[0.969924,0.00873352,0.003329221,0.001003827,0.000848243,0.0133491,0.0004393718,0.00001988387,0.002352829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007657279,"threshold_uncertainty_score":0.02561617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07076856362050964,"score_gpt":0.3846002729822743,"score_spread":0.3138317093617647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}