{"id":"W2046100401","doi":"10.1097/mpg.0000000000000179","title":"Lynch Syndrome","year":2013,"lang":"en","type":"review","venue":"Journal of Pediatric Gastroenterology and Nutrition","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Lynch syndrome; PMS2; MSH6; Medicine; MLH1; MSH2; Germline mutation; DNA mismatch repair; Population; Genetic testing; Cancer; Genetic counseling; Colorectal cancer; Genetics; Family history; Mutation; Internal medicine; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001568286,0.0007069532,0.0006175137,0.001203637,0.000331606,0.0004982772,0.0004590219,0.0008130927,0.01202577],"category_scores_gemma":[0.0007155481,0.0001058319,0.0002836431,0.000721688,0.000292993,0.0004310943,0.0005105184,0.0008095144,0.005318775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002553546,"about_ca_system_score_gemma":0.0004859232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008716593,"about_ca_topic_score_gemma":0.001428029,"domain_scores_codex":[0.9998615,0.00002526211,0.00001973005,0.00002886017,0.00004000374,0.00002457726],"domain_scores_gemma":[0.9998326,0.000062899,0.00003424054,0.00000722072,0.00003500039,0.00002794706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008211468,0.00003244443,0.001605001,0.003684894,0.00008262757,0.006833089,0.0001198024,0.0001319426,0.002288837,0.003388888,0.1302711,0.8514792],"study_design_scores_gemma":[0.00002789376,0.0000455283,0.002150477,0.001823373,0.00007109179,0.0486081,0.00008497058,0.00004424735,0.0005057132,0.001387411,0.9452363,0.00001492013],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002092369,0.9626325,0.001444678,0.001913378,0.001673068,0.0000442424,0.0004483445,0.0001636845,0.02958764],"genre_scores_gemma":[0.04093865,0.9200751,0.00285231,0.003741723,0.002100351,0.00008031667,0.00181737,0.00004086914,0.02835335],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01202577,"threshold_uncertainty_score":0.04023021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03211951077106175,"score_gpt":0.3105914067949492,"score_spread":0.2784718960238875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}