{"id":"W2046138985","doi":"10.1126/science.1152066","title":"Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization","year":2008,"lang":"en","type":"article","venue":"Science","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1111,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Hospital for Sick Children; St. Michael's Hospital","funders":"","keywords":"Phosphatidylserine; Endocytic cycle; Phospholipid scramblase; Endosome; Cytosol; Membrane; Cell biology; Membrane protein; Chemistry; Transmembrane protein; Endocytosis; Surface charge; Phospholipid; Exocytosis; Biophysics; Biochemistry; Biology; Cell; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001264557,0.00008031063,0.00006560636,0.00001878291,0.0002105601,0.00001598934,0.0001332204,0.00004148787,0.00002785592],"category_scores_gemma":[0.00003784775,0.00006631176,0.00001438813,0.0001859965,0.0004364971,0.0000118023,0.00007182255,0.00002919944,0.000005181319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004907887,"about_ca_system_score_gemma":0.00007501993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001117218,"about_ca_topic_score_gemma":0.000003981645,"domain_scores_codex":[0.9992875,0.000009069578,0.0000833243,0.0002942405,0.0001511346,0.0001747301],"domain_scores_gemma":[0.9996329,0.000001098325,0.00003188016,0.0001908699,0.00006922203,0.00007403362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006779675,0.000009170327,0.001854782,0.0000063422,0.000001105387,0.000001530795,0.00003722137,0.00001489312,0.997681,0.00003801437,0.00004885955,0.0003002947],"study_design_scores_gemma":[0.0001670985,0.00006708045,0.003543628,0.000004713759,0.000002471132,0.00004004633,0.000006289369,0.0001582237,0.9899741,0.000003691427,0.005936919,0.00009576131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991411,0.0001348287,0.00009795516,0.00006520754,0.000100211,0.0001494292,0.000003035369,0.0000116013,0.0002966202],"genre_scores_gemma":[0.9973635,0.0000967591,0.0004082111,0.00008824337,0.00008600816,0.00000366707,0.00001336565,0.000006261509,0.001933957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007706929,"threshold_uncertainty_score":0.2704115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008252205684900208,"score_gpt":0.2287543814640932,"score_spread":0.220502175779193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}