{"id":"W2046138985","doi":"10.1126/science.1152066","title":"Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization","year":2008,"lang":"en","type":"article","venue":"Science","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1111,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Hospital for Sick Children; St. Michael's Hospital","funders":"","keywords":"Phosphatidylserine; Endocytic cycle; Phospholipid scramblase; Endosome; Cytosol; Membrane; Cell biology; Membrane protein; Chemistry; Transmembrane protein; Endocytosis; Surface charge; Phospholipid; Exocytosis; Biophysics; Biochemistry; Biology; Cell; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001302168,0.0002297316,0.0001301516,0.0002098875,0.0001590227,0.000562944,0.0001674399,0.0002876557,0.00106902],"category_scores_gemma":[0.0002114759,0.0001106413,0.0001176912,0.0001564185,0.0002908439,0.0003362481,0.0002816109,0.0002830817,0.0006113528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003597093,"about_ca_system_score_gemma":0.0001405562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002710928,"about_ca_topic_score_gemma":0.0003118431,"domain_scores_codex":[0.99988,0.00001937904,0.000004927136,0.00002475778,0.00003139817,0.00003960623],"domain_scores_gemma":[0.9998395,0.00003002363,0.00003854511,0.00001121427,0.00003972591,0.00004100946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004488879,0.000005527762,0.0002385301,0.000007395298,9.939677e-7,0.00002575616,0.000009973913,0.00002330331,0.9986265,0.0001210026,0.0000167973,0.0008793529],"study_design_scores_gemma":[0.00001085387,0.00006346942,0.01380959,0.000003681294,0.000007168236,0.0002441716,0.00005794752,0.001463819,0.9827995,0.0002680713,0.001265696,0.000005850561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995551,0.0008592204,0.001797587,0.00008164177,0.00001037813,0.00000473206,0.00005886103,0.00004328608,0.001593374],"genre_scores_gemma":[0.9972519,0.0004385057,0.0005023124,0.00002123276,0.000005247067,0.00000401787,0.00007297873,0.00001543033,0.001688338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00106902,"threshold_uncertainty_score":0.003576219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008252205684900208,"score_gpt":0.2287543814640932,"score_spread":0.220502175779193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}