{"id":"W2046149237","doi":"10.1002/hup.1073","title":"Augmentation of atypical antipsychotics with valproic acid. An open‐label study for most difficult patients with schizophrenia","year":2009,"lang":"en","type":"article","venue":"Human Psychopharmacology Clinical and Experimental","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Astellas Pharma; Asahi Kasei Pharma Corporation; GlaxoSmithKline; Dainippon Sumitomo Pharma; Pfizer","keywords":"Brief Psychiatric Rating Scale; Risperidone; Clozapine; Polypharmacy; Olanzapine; Schizophrenia (object-oriented programming); Clinical Global Impression; Medicine; Valproic Acid; Sedation; Internal medicine; Adverse effect; Global Assessment of Functioning; Positive and Negative Syndrome Scale; Psychiatry; Pediatrics; Psychosis; Anesthesia; Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002137442,0.0002683194,0.0005859407,0.00008615218,0.0002338018,0.00004098868,0.0001998288,0.0001053955,0.0001310346],"category_scores_gemma":[0.0000162634,0.0001747062,0.00004019219,0.000169537,0.0003630027,0.0001739897,0.00004791512,0.0002500908,0.000004421065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003270284,"about_ca_system_score_gemma":0.00009938215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005077816,"about_ca_topic_score_gemma":0.000020401,"domain_scores_codex":[0.9980174,0.0001425216,0.0005717517,0.0006535409,0.0003042102,0.0003106058],"domain_scores_gemma":[0.9987712,0.00007191201,0.0001698628,0.0002731315,0.0001939331,0.0005199441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7376043,0.07249626,0.1653274,0.00001792574,0.0006247252,0.00004062531,0.0003368259,4.689539e-7,0.01274349,0.0002411719,0.0008851306,0.009681582],"study_design_scores_gemma":[0.2565444,0.09405044,0.6454819,0.00003410627,0.0002773359,0.00001015605,0.0003632467,0.0000375533,0.002887262,0.0001142714,0.00001557057,0.0001837523],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956774,0.0001183083,0.00001798267,0.0002612496,0.000127996,0.003688294,0.00002813524,0.00003404862,0.00004657824],"genre_scores_gemma":[0.9934614,0.00001223078,0.005322823,0.0005971516,0.0001458609,0.0002047426,0.0001844911,0.00002646538,0.00004483478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4810599,"threshold_uncertainty_score":0.7124313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08173536920673692,"score_gpt":0.4752615703145118,"score_spread":0.3935262011077749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}