{"id":"W2046188448","doi":"10.4161/cc.9.5.11156","title":"Deregulation of innate immune signaling in myelodysplastic syndromes is associated with deletion of chromosome arm 5q","year":2010,"lang":"en","type":"editorial","venue":"Cell Cycle","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Biology; Innate immune system; Myelodysplastic syndromes; Signal transduction; Immune system; Chromosome; Genetics; Deregulation; Immunology; Cancer research; Cell biology; Bioinformatics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003624489,0.0002832327,0.0007709479,0.0003465201,0.00005550404,0.000008652002,0.0002626113,0.001430148,0.0007257406],"category_scores_gemma":[0.0003966827,0.0002563279,0.0001200806,0.0002097419,0.0002515256,0.00007302268,0.0000682438,0.0009711938,0.00004927244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008463214,"about_ca_system_score_gemma":0.0002488774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002402814,"about_ca_topic_score_gemma":0.00004408479,"domain_scores_codex":[0.998337,0.0002624829,0.0006895565,0.0002935783,0.0001097363,0.000307593],"domain_scores_gemma":[0.997817,0.0008084901,0.0007672972,0.0002910445,0.0003041615,0.00001200553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009049327,0.0003317835,0.00005444336,0.0001885553,0.0002156479,0.000006040453,0.000533974,0.00004732031,0.9849843,0.000005792879,0.01247506,0.0002521066],"study_design_scores_gemma":[0.002616547,0.0009349181,0.001280514,0.001054646,0.000144348,0.000007963157,0.00009073314,0.00001889704,0.9819188,0.0000401971,0.01156431,0.0003281653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.874728,0.001746443,0.00001927232,0.00001024205,0.1227664,0.0002228003,0.000135999,0.00002537451,0.0003454674],"genre_scores_gemma":[0.9935555,0.00009310558,0.00001740911,0.000003865824,0.003378448,0.00001338822,0.0009850084,0.00004439479,0.001908881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.119388,"threshold_uncertainty_score":0.9999889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005268120673409291,"score_gpt":0.2151733079908467,"score_spread":0.2099051873174374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}