{"id":"W2046200381","doi":"10.1016/j.carres.2007.05.014","title":"Zwitterionic glycosidase inhibitors: salacinol and related analogues","year":2007,"lang":"en","type":"review","venue":"Carbohydrate Research","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Chemistry; Sulfonium; Stereochemistry; Computational biology; Glycoside hydrolase; Combinatorial chemistry; Thio-; Drug candidate; Drug discovery; Biochemistry; Enzyme; Organic chemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.002272378,0.001016945,0.00235806,0.0009329797,0.000489271,0.0004134228,0.0008894454,0.001984173,0.00127711],"category_scores_gemma":[0.0006827172,0.0009055941,0.000770559,0.00197988,0.0009441124,0.0001697144,0.000761286,0.003457985,0.000420651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007817753,"about_ca_system_score_gemma":0.0007281708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009954564,"about_ca_topic_score_gemma":0.0000107329,"domain_scores_codex":[0.993534,0.0004167201,0.001503745,0.001644899,0.001195755,0.001704848],"domain_scores_gemma":[0.9951773,0.001718126,0.0003711885,0.001617164,0.0003571152,0.0007591464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003473513,0.0001471565,0.000006005611,0.04363757,0.0006513163,0.001734805,0.0001762537,2.425921e-7,0.03329743,0.000127302,0.001028859,0.9191583],"study_design_scores_gemma":[0.0003321645,0.00003388805,3.027278e-7,0.01906294,0.0005187413,0.0003338073,0.0001774292,0.00001964536,0.01682846,0.0002986026,0.9612318,0.001162188],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00628182,0.9649094,2.96565e-7,0.00003640672,0.0001809532,0.0004057905,0.0001468332,0.000241451,0.02779707],"genre_scores_gemma":[0.004488694,0.988446,0.00001206845,0.000006728521,0.0007734546,0.0002432962,0.000622332,0.0002462901,0.005161162],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.960203,"threshold_uncertainty_score":0.9996359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1452082992091737,"score_gpt":0.4067711509237879,"score_spread":0.2615628517146142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}