{"id":"W2046236198","doi":"10.1038/461743a","title":"Tracing Argonaute binding","year":2009,"lang":"en","type":"letter","venue":"Nature","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Argonaute; RNA-induced silencing complex; Trans-acting siRNA; RNA; Dicer; Thermus thermophilus; RNA-induced transcriptional silencing; Biology; Cell biology; Gene silencing; RNA silencing; Small RNA; Small interfering RNA; RNA interference; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00174929,0.0004503858,0.0006168687,0.0003848594,0.001952658,0.001842645,0.001040838,0.009995949,0.00374722],"category_scores_gemma":[0.005344756,0.0004754399,0.0005335868,0.0002039928,0.00213753,0.00166441,0.001460814,0.01329301,0.002525909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002198769,"about_ca_system_score_gemma":0.0008382741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001431082,"about_ca_topic_score_gemma":0.002959986,"domain_scores_codex":[0.9992261,0.0001451719,0.00005327827,0.0001329082,0.000324242,0.0001183423],"domain_scores_gemma":[0.9985775,0.0006605202,0.00008290782,0.0001652576,0.0002541963,0.0002597853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003288124,0.00005860052,0.0005653098,0.0001289403,0.00003765202,0.001425587,0.0001356733,0.0003717989,0.01485504,0.03745718,0.8970582,0.04757725],"study_design_scores_gemma":[0.0001236763,0.00009152418,0.000604248,0.00005358313,0.00004125625,0.001390707,0.000105976,0.002044299,0.02018599,0.032501,0.9428182,0.00003956579],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.008269665,0.02245196,0.008246098,0.8443977,0.09183466,0.00004339367,0.000240294,0.0004960642,0.02402019],"genre_scores_gemma":[0.1401714,0.01437468,0.01033166,0.6852118,0.03960381,0.00016411,0.0002316005,0.0001684416,0.1097426],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009995949,"threshold_uncertainty_score":0.01595324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00781624315003896,"score_gpt":0.2752449710081789,"score_spread":0.2674287278581399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}